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Re: Initiating Metformin

From: click (anonymous@obgyn.net)
Wed, 27 Aug 2003 10:16:01 -0500 (CDT)

I went to my new general practitioner because of my rapid weight gain (unexplained; ate very little), my low energy, missed period for mroe than a year, etc.. I was 16 years old, 5'7, 240 lbs, blood pressure was 170/100.

The Dr ordered blood work checking a couple types of testosterone levels, sugar levels, lipid levels, and some other items.. after that, my GP suspected PCOS--she sent me to a gynocologist & an endocronologist. I got into the gyno first. The gyno did an exam as I'd never had one before--to check for abnormalities because of my high testosterone, and then sent me to have an ultrasound of my ovaries done (non vaginal as I was a virgin) to rule out any large cysts or abnormal sizing. All that came back OK, but I still haddn't had a period, so my gyno put me on high doses of progesterone for 5 days and I had a 30 day long period. About two weeks into that, I demanded to start the insulin resistance treatment I'd been suspected of having since I haddn't been able to get into the endocronologist yet and my weight was getting worse, so my gyno perscribed me enough for a month to hold me over. The endocronologist had ultrasounds of my kidneys done, a CAT of my adrenal glands, etc to rule out any other causes of my symptoms and things that would be problems with the medication. Also, my blood pressure after a few weeks of the metformin had dropped to 150/90--a large improvement. All of the tests came back normal and he continued my glucophage treatment and continued communicating with my gynecologist.

Two months later I had realized that the medication's side effect that were only to last the adjustment period were still plaguing me and really crippling my life (in bed after 5pm because of stomach pain/cramps, cold sweats, up and down blood sugar & moods) and so my endocronologist switched me to glucophage XR (time release) and it was magic. Two months later I'd lost 12 pounds or so, by 6 or 7 months I had lost 40 pounds--all without effort--eating the same as I had before I was diagnosed (which was not bad, btw, except for soda which was not in excess)

... anyway, That's the summed up version of events.

At Wed, 27 Aug 2003, anonymous@obgyn.net wrote: >
>A doctor should take blood to run the following; FSH (Follicle
>Stimulating Hormone), will be normal or low with PCOS,LH (Lutenizing
>Hormone), will be elevated with PCOS,LH/FSH greater than 2:1 or 3:1 may
>be considered diagnostic of PCOS, Prolactin can be normal or low with
>PCOS ,Testosterone, total and/or free usually elevated with PCOS,DHEAS,
>frequently mildly elevated with PCOS , Estrogens, may be normal or
>elevated with PCOS , Lipid profile (low HDL, high LDL, and cholesterol,
>elevated triglycerides) Glucose, may be elevated, Insulin, often
>elevated with PCOS ,TSH (Thyroid stimulating hormone) some who have PCOS
>are also hypothyroid
>
>I had the initial blood test that checked most of the above and then I
>had the glucose tolerance test to rule out diabetes.
>
>Also, they did a vaginal Ultrasound to evaluate cysts/enlarged ovaries.
>
>Hope this helps.
>
>At Tue, 26 Aug 2003, anonymous wrote:
>>
>>I'd like to hear from anyone about how their doctor came to place them
>>on Metformin/glucophase. Was it the results of blood tests, if so which
>>ones?
>>Thanks

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