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Re: metformin and pregnancy

From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Wed, 7 May 2003 06:40:40 +0200

Hi Lara,

I can't comprehend: were you on metformin AND BCP? Although insulin sensitizers (like metformin) are the treatment for the metabolic dsisorder at the core of PCOS, other issues have to be taken into account too. So before starting on metformin again, you should have an endocrine work-up. Have you had one? In my opinion metformin should be dosed much more cautiously for PCOS, 3000 mg seems to me extremely high. Most of your problems seem to be side effects of this high dose.

Sam

> I have been on metformin (glucophage) - started off 1000mg nothing
> happened for one whole year and ALL symptoms became worse (hair, weight,
> acne, no periods for 18 months)
> Have now come off the bcp and am now taking 3000mg metformin daily since
> past couple of weeks and feel extremely sick and nauseous and sometimes
> very dizzy too.
> Has anyone else taken the same dose of metformin ? Did the hair and acne
> and general testosterone levels improve ?
> Also I would like to know if the sickness and dizziness is normal on
> metformin- would appreciate any advice especially from Dr Sam.
>

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