Dr Sam --- can you clarify a couple of things
From: Anna (anonymous@obgyn.net)
Mon, 21 Apr 2003 19:00:17 -0500 (CDT)
Dr. Sam,
What do you mean by low dosage Metformin ( I am supposed to be taking
500mg, 3 times a day - acutally I am having side effects so I am
breaking the pill in half and gradually plan to increase). Is 500mg x 3
low dosage?
We plan to get pregnant in the next 1-2 months after I lose a bit more
weight.
I am very nervous about taking Metformin during pregnancy as this
medication passes over to the baby. I hope to switch to insulin after I
get pregnant.
Could you tell me if Metformin is considered safe? Which one is safer
out of Metformin and Insulin.
You say: "Although pregnancy loss may have numerous causes, yours may
have been influenced by your insulin resistance". Could you tell me how
it could have been affected by insulin resistance.
Thanks,
Anna
At Sun, 20 Apr 2003, =?iso-8859-2?q?Zalányi wrote:
>
>Hi Anna,
>As I have steressed in several letters earlier, PCOS is a bunch of symptoms and not everyone has all of them (fortunately).
>You seem to have PCOS based on your symptoms and lab. values. I think, you would definitely benefit from taking low dose metformin and continuing on it during pgy. Although pregnancy loss may have numerous causes, yours may have been influenced by your insulin resistance.
>Good luck and inform me about your progress
>
>Sam
>
>> Dr. Sam,
>>
>> I am 29 years old and have regular periods. I mean I have periods every
>> month - and I think I ovulate as well. Initially my cycles used to be
>> 25-28 days for a good few years (15 years) then later on with my job,
>> stress, weight gain, etc they became 28-32 days for about 3 years. But
>> its never been that I have not had a period.
>>
>> Once we TTC, I conceived immediately. Symptoms I have are:
>>
>> - Severe insulin resistance
>> - Was on insulin during pregnancy
>> - Acne on upper arms
>> - mild facial hair growing only in last 2 years
>> - hair loss
>> - my testosterone levels are higher .. right now at about 60
>> - cholesterol high, Cardio CRP high
>> - currently overweight, was obese for 2 years
>>
>> Looking forward to your advice.
>>
>> Thanks,
>> Anna.
>>
>> At Fri, 18 Apr 2003, =?iso-8859-2?q?Zalányi wrote:
>> >
>> >Hi Anna,
>> >
>> >What do you mean by mild PCOS: what symptoms do you have?
>> >How old are you? You may simply have been lucky with easy conception and
>> >PCOS may strike in full force later on.
>> >Looking forwasrd to your answers
>> >
>> >Sam
>> >
>> >> I recently started on Metformin as prescribed by my doctor and I have
>> >> "mild" PCOS.
>> >>
>> >> Lost my pregnancy in my 5th month during which I had gestational
>> >> diabetes and wsa on insulin. Endo has started me now on Metformin.
>> >> However one thing is that although I know I am taking Metformin to keep
>> >> my sugar levels in optimal condition before I try to get pregnant, I am
>> >> confused seeing posts about infertility/PCOS. I conceived immediately,
>> >> have regular periods but have severe insulin resistance.
>> >>
>> >> Just want to make sure I am Metformin is the way to go prior to TTC
>> >>
>> >> Thanks.
>> >> Anna
>> >>
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