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no subject received Tue, 25 Mar 2003 13:32:38 -0600

From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Tue, 25 Mar 2003 06:40:11 +0100

Hi Sherry,

Actually this is very typical for PCOS and here is why: During months or years of unsuccessful (unovulatory) cycles, the unovulated follicles remain in the ovary increasing its volume. Plus the outer layer of the ovaries thickens. Actually this thickening may be the ultimate cause of anovulation, b/c the egg can not break through it. Now if you take clomid, which causes more than one follicle to grow and grow more agressively, they turn into cysts. This is why I keep saying, that metformin is the first step in ovulation induction for PCOSers, and even if not successful, you should combine clomid with metformin. For your info

Sam

> I have posted once before on this forum. I will keep you all posted if
> metformin does the trick getting me pregnant.
>
> I have one other question. In my 2 year pursuit to get pregnant, I have
> been on/off Clomid for over a year. The Clomid makes me ovulate
> succesfully. However, one unfortunate side-effect is that I get
> hyperstimulated (well, my ovaries do). They get extremely enlarged, and
> huge cysts form on my ovaries and then the doctors tell me to take a
> break off of the Clomid. We watch them with ultrasound for a few
> cycles, and then it goes away, and I get back on.
>
> I am wondering how common is this? Was this a weird reaction that only I
> had on Clomid? If so, is this PCOS reaction to Clomid, or just a rare
> reaction that anyone can have to the Clomid...
>
> I'm wondering because if metformin doesn't work for me, what other
> options do I have, other than IVF?
>
> --
> --sherry
>

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