PCOS-MEDICATION Messages for March, 2003: Re: Pregnancy and progesterone

Re: Pregnancy and progesterone

From: Cassandra (anonymous@obgyn.net)
Sun, 9 Mar 2003 20:24:45 -0600 (CST)

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At Sun, 9 Mar 2003, BJ wrote: >
>The Arbonne site is the best I've found that specifically addresses
>progesterone and pregnancy and mentions studies.

I can't get into the website you posted. The http://www.arbonn-central.com/detail2.asp?product_ID=FYI-14. link gives me a 404 error message, and when I try http://www.arbonn-central.com/ or http://www.arbonne-central.com (in case it was misspelled) I get a message stating I am not authorized to view this page, or a pop-up window asking for a password. Could you re-post a link that is open to the public? I'd like to see the studies.

>The NPAN site is the
>best I've found for overall info on use of progesterone. By the way,
>their e-book gets very specific about dosing regimens for various
>conditions but the info is based mostly on the real-life experience of
>women using progesterone creams.

The testimonials won't do it for me. I'm a basic science type of gal....

>As for studies, I have been using P cream (several different brands, but
>mostly one, notice I don't mention names unless asked!) for almost 9
>years now and I have seen first hand the benefits. As someone who once
>worked in medical research and saw doctors faking data to publish, I
>don't necessarily trust what I read in medical journals, especially
>considering the politics of alternative treatments versus pharmaceutical
>companies (who fund a great deal of the research).

As someone who has also participated in research (albeit on the clinical end collecting data, rather than the publishing or writing end) I agree that there are a few bad apples out there, but I'd hate to paint all medical research with the same broad brush. We've got to be able to trust some research, and if there is a review article done without pharmaceutical industry support, or a Cochrane review, I tend to trust the findings. I also take offense that someone might look upon data that I collected as "faked." I can assure you I've never done anything of the sort!

>
>You know, it seems a bigger issue with the Prometrium is the variance in
>the dosing, depending on how well your liver is working any particular
>day.

This is true for any p.o medication, not just P4. But there comes a time that you have to trust pills for certain things, and when I need something that can be stored at room temp. while I'm out of town, a p.o. form sounds like a better option. I have heard less than enthusiastic things about bio-adhesive gels, but they could be stored at r.t also, and perhaps the dosing switch from one intravaginal form to another would be more straightforward.

>Since I don't know what you're using it for or what dose I
>think your best bet for switching delivery systems is to talk to a
>compounding pharmacist.

Agreed. I don't have the experience to figure it out on my own (I'm not in GYN or endo,) my RE is chronically out of town, and his office is not very helpful when I have questions. Perhaps the pharmacist who makes my current suppositories could help me here.

>I'm sorry if I sounded a little testy in my response. I have been
>"jumped" before and accused of selling product on these boards. Guess
>I'm a little sensitive about that issue! I have just had such amazing
>success with P that I feel I need to at least let other women know there
>are options.

Likewise, I sometimes feel I am being "jumped" for being on the side of Western medicine as opposed to herbals. I just like to see reproducible, non-biased data on something before I use it. When I look up the P4 creams, most of the "data" comes from Dr. Lee, whom I suspect is just a tad biased himself. Do you have any research done by other people?

>I'll be curious to know what you decide to do about your travel plans.
>BJ

I'll let you know if I get back online before I leave.

--
Cassandra

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