Re: Met vs Actos/Avandia - Antoher Quest to Dr. Sam
From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Mon, 27 Jan 2003 06:01:23 -0800
Hi Sally,
Although fasting glucose and insulin arre only very rough measures of glucose metabolism, your weight loss and improving cholesterole profile are promising. Therefore I wouldn't expect any dramatic improvement from changing an insulin sensitizer to another.
As for what steps to take next, depends on yor wishes (regular cycle, ovulation, pgy?)
For your info
Sam
> Hi Doc Sam,
>
> always like reading your comments. Thankyou. Another Met vs. Avandia q.
>
> My endocrinologist wants me to try avandia - instead of met. The reason
> is that on met I am still not having 'periods' - only very minor
> spotting that last 2 days - this is with diane or provera. Haven't
> tried a non-drug cycle for about 6 months - but then was next to nothing
> - hence using provera or diane. Diane gives great skin problem
> management! I did have 'normal' periods when I was a teenager lasting 3
> - 4 days.
>
> On last testing fasting insulin and glucose low normal. I have also
> lost 50 lbs over the past two years (in fits and starts but no regains)
> through strict dieting and regular intensive exercise and my weight
> could be considered almost normal (156 lb, 5'5"), lipid profile
> dramatically better (HDL increased from about 20 to 35, and everything
> else went down, total now below normal range), hypothyroid is usually
> well controlled, feel very much better .....
>
> Would trying avandia rather than met be worthwhile. Or could there be
> other possible non-pcos cause/s that should be investigated first. My
> dr. is great, but she is an endocrinologist - not a obgyne. Other than
> annual paps and ultrasound (for the past few years) have never had any
> sort of gynecological work up or investigation.
>
> Also I am reluctant to try avandia becuase of the cost (I have to pay
> myself and met costs only P32 each day whereas Avandia would cost P170 -
> that is Philippines Peso), plus the liver monitoring that needs to be
> done (more cost and also potential risk).
>
> Sorry this is long. But would appreciate your comment.
>
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