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Met vs Actos/Avandia - Antoher Quest to Dr. Sam

From: sally (anonymous@obgyn.net)
Sun, 26 Jan 2003 20:43:21 -0600 (CST)


Hi Doc Sam,

always like reading your comments. Thankyou. Another Met vs. Avandia q.

My endocrinologist wants me to try avandia - instead of met. The reason is that on met I am still not having 'periods' - only very minor spotting that last 2 days - this is with diane or provera. Haven't tried a non-drug cycle for about 6 months - but then was next to nothing - hence using provera or diane. Diane gives great skin problem management! I did have 'normal' periods when I was a teenager lasting 3 - 4 days.

On last testing fasting insulin and glucose low normal. I have also lost 50 lbs over the past two years (in fits and starts but no regains) through strict dieting and regular intensive exercise and my weight could be considered almost normal (156 lb, 5'5"), lipid profile dramatically better (HDL increased from about 20 to 35, and everything else went down, total now below normal range), hypothyroid is usually well controlled, feel very much better .....

Would trying avandia rather than met be worthwhile. Or could there be other possible non-pcos cause/s that should be investigated first. My dr. is great, but she is an endocrinologist - not a obgyne. Other than annual paps and ultrasound (for the past few years) have never had any sort of gynecological work up or investigation.

Also I am reluctant to try avandia becuase of the cost (I have to pay myself and met costs only P32 each day whereas Avandia would cost P170 - that is Philippines Peso), plus the liver monitoring that needs to be done (more cost and also potential risk).

Sorry this is long. But would appreciate your comment.




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