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Re: Glucophage (metformin) and yeast infections

From: carlene (anonymous@obgyn.net)
Wed, 15 Jan 2003 23:09:57 -0600 (CST)


At Wed, 15 Jan 2003, =?iso-8859-2?q?Zalányi wrote: >
>Hi,
>
>I was wondering about the coincidence of recurrent yeast infections and metformin medication and it simply didn't add up...
>Yeast infections are common in diabetics, so it would make sense that PCOSers (being IR) would have more frequent yeast infections than other women. But it was contradicting common sense that having your glucose metabolism regulated would sensitize you for yeast infections. So I put it away as an individual story without relevance for PCOS. Then other ladies turned up with the same story which made me thinking again and it popped up.
>Metformin is known to deplete folic acid in the body (probably due to malabsorption) and this is the clue to yeast infections or vaginal infections in general: Lactobacilli need folic acid for their proper development and for ensuring optimal pH in the vagina. So if their is less than optimal amount of folic acid, Lactobacilli suffer and pathogens may overcome them.
>Therefore I think, instead of omitting metformin from your medication, you should try folic acid supplementation. I would be interested if any of you would try and tell me her experiences.
>For your info
>
>Sam

DR.SAM HI. thought I'd tell you I used to have horrible yeast infections. I'm diabetic on glucophage, My DR. told me to take folic acid among others,I haven't had another yeast infection since,always thought it was because meds got my sugars under control.I also have pcos.




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