|
Re: metformin and long tern affects
From: kim (anonymous@obgyn.net)
Sat, 28 Dec 2002 09:40:53 -0500
The ideal amount of metformin if TTC is 1500mg a day, minimum. I take 2500mg a day.
KIM(30 SOMETHING)dh SCOTT- JUST A BABE AT ONLY 30 
DX - PCOS/IR, hyperinsulinenmeia, thyroid failure, depression, infertility with repeated m/c.
7m/c's . TTC#1 - forever!!! Last 7 years straight with IF meds till May 2002. Dec 2002 - back on clomid 100mg for 3 months.
Recurrent m/c specialist results useless. Being referred to PCOS specialist - 2003
Meds - Metformin 2500mg, 10mg synthyroid, 300mg wellbutrin, 100 mg clomid, 81mg daily asprin, materna, 1mg folic acid, extra vitamans C&E&daily.
>From: Carmela Kappel
>Reply-To: anonymous@obgyn.net
>To: Multiple recipients of list PCOS-MEDICATION
>Subject: Re: metformin and long tern affects
>Date: Fri, 27 Dec 2002 15:56:51 -0600
>
>What dosage of Metformin are you taking? I'm on 500 mg and it doesn't seem to be helping. Should I increase to 1000 mg?
>Thanks.
> Le Anna wrote:I don't know about long term effects of Metformin. My doctor hasn't
>seemed too worried about it when I've brought it up. I have never liked
>taking medications unless absolutely necessary, so the diagnosis of PCOS
>threw me for a loop. I've been taking Metformin/Glucophage for close to
>2 years now and I have to say that it's been a lifesaver. Prior to
>taking it, my mood swings were awful (my poor husband) my monthly cycles
>were very irregular and my weight gain was horrendously centered around
>my stomach and I couldn't lose an ounce no matter what I did.
>Thankfully, the mood swings have toned down a LOT..usually only bad
>around my periods, I've lost 40 lbs and my cycles are back to being on
>time (almost to the minute).
>
>The other "problem" I was told that I may have is Endometriosis. I had
>an episode December 2001 that sent me to the ER. I had some kind of
>"explosion" in my stomach area that had me convinced I was having a
>stroke or an aneurysm. I couldn't move my arms, couldn't walk or talk,
>and was flat on the floor on my stomach until the ambulance came. Once
>in the ER, my white cell count was sky high and they ran all kinds of
>stomach tests, MRI's & x-rays on me but couldn't find a thing wrong. I
>kept telling them about the PCOS and of course they didn't check
>anything and sent me home after 8 hours. I went to my regular dr. as a
>follow up a week later (when I could finally walk) and they ran all
>kinds of ultrasounds & xrays as well. Couldn't find evidence of any
>ovarian cysts, gall stones, kidney stones...nothing. Could tell me
>everything I DIDN'T have, but nothing definitive as to what it WAS.
>Since then, my periods have become increasingly painful & heavy. Until
>my OB/GYN can do a laproscopy (insurance issues), he won't know for sure
>if it IS endometriosis. For now, I deal with the pain the best I can.
>
>As for fertility issues: my dr. told me that many women have PCOS and
>don't know it until they can't become pregnant. They go to the dr. to
>find out why they can't conceive and learn all about PCOS. The reason
>Metformin is prescribed is that PCOS causes weight gain around the
>mid-section of the body which in turn can make people diabetic (or they
>are considered pre-diabetic at diagnosis). PCOS causes high levels of
>testosterone in the system which can affect the function of the pancreas
>& ovaries. The more the pancreas, testosterone & PCOS are of control,
>the more the symptoms happen and the more the periods are messed up.
>That's why when Metformin is prescribed, it lessens the symptoms, the
>pancreas starts working properly (causes easier weight loss), the
>testoserone levels out & periods become more normal. Which also helps
>with the mood swings & fertility.
>
>Hope all of this helps. I wouldn't say that Metformin is a cure-all for
>ALL of your symptoms, but it has helped me. I've tried going off of it
>for awhile and the mood swings and messed up cycles were too much for me
>to handle.
>
>Take care everyone & may God bless your health.
>
>Carmela Kappel
>
|
|
![[ PCOS Discussion Forums ]](../../images/pcos_at_obgyn.gif)