Re: Metformin Help!
From: Gill (anonymous@obgyn.net)
Thu, 12 Dec 2002 13:47:14 -0600 (CST)
How do we know which brand we are on? Is it manufacturer based? Can we
ask our doctor to only prescribe that brand (UK based question)?
Has any research been carried out on the bioequivalent differences on
this or other drugs? I too have experienced some differences with cycles
and just assumed that Metformin was the same from manufacturer to
manufacturer.
At Thu, 12 Dec 2002, Sheleigh wrote:
>
>I did a bit of research on the difference between generic and name brnad
>drugs and found this:
>A drug may be chemically exact but not bioequivalent. In other words,
>two different products of the same drug may not get into the body in
>exactly the same way. Bioequivalence depends on how the drug is
>formulated and how it is absorbed and eliminated by the body. Other
>ingredients can affect the absorption of the drug. These include starch
>fillers, gum-like substances and other products which allow a drug to be
>formulated into a pill or capsule. Factors such as a person's age, body
>mass, kidney, liver and intestinal function can also affect the
>absorption of the drug by the body.
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