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Re: Glucophage XR==GI side effects....help!!

From: Diandra (anonymous@obgyn.net)
Mon, 7 Oct 2002 21:42:41 -0500 (CDT)


At Sun, 24 Feb 2002, Lori wrote: >
>I am experiencing the same prorblem with what looks like the capsules
>coming out. I did a science experiment on it today, and it isn't solid
>on the inside. I am wondering if it is perhaps fat that we are passing
>directly? I have been taking it for about 5 months and my GI problems
>have never stopped. They have gotten better as time has passed but a
>regular stool is still something very rare for me. I decided that it
>was better than not treating it, so I just drink plenty of water each
>day and bear it, although it does get embarassing sometimes.
>
>At Sun, 24 Feb 2002, claire wrote:
>>
>>At Fri, 22 Feb 2002, mrsdoubtfyre wrote:
>>>
>>>At Mon, 18 Feb 2002, =?iso-8859-2?q?Zalányi wrote:
>>>>
>>>> <madeline808@aol.com (Maddy)> 2002.02.17. 22:52:40 -6h-kor írta:
>>>>Come on Maddy,
>>>>
>>>>If you have GI side-effects, then the substance is absorbed. It is only the outer shell you find 9-12 h later in stool. Regular metformin is even worse as for side-effects.
>>>>For your info
>>>>
>>>>Sam
>>>>Hi there
>>
>>Ijust wanted to let you know that I too have had great success with
>>AlkaSeltzer, and within about 10 mins of taking one, all my stomach
>>cramps disappear. I have also found that following a low fat diet
>>incredibly successful with both the GI symptoms of met, and also weight
>>loss (i've lost 24lbs in 2 months)
>>
>>hope you're problems improve, I know how painfull they can be, but dont
>>give up, it's all worth it in the end
>>
>>good luck
>>
>>Claire
>>>>> Hi there--
>>>>> I'm 25 and just started on Glucophage XR. I have been taking 500 mg.
>>>>> for about a week, and I am having pretty awful GI upset....diarrhea etc.
>>>>> Also, i saw someone else with this problem, the capsules themselves
>>>>> sometimes come out, but like nine to twelve hours later!!! Someone
>>>>> replied that the medication itself is absorbed, but how can that be? I
>>>>> actually checked one of the undigested capsules and there was a white
>>>>> substance inside. Does anyone think regular Glucophage is easier to
>>>>> digest, etc. than the Glucophage XR? I have been taking it with my
>>>>> dinner....so I don' tknow what to do about the stomach upset and how
>>>>> long to stick it out. I want to get up to 1500 mg.
>>>>>
>>>>> Any tips or advice would be greatly appreciated. I really do want to
>>>>> stay on it..i was on Avandia but developed some serious edema.
>>>>>
>>>>> Thanks so much.
>>>>>
>>>>> maddy
>>>>>
>>>Dear Maddy: I found that an AlkaSelzer tablet taken once a day for a
>>>week or
>>>so removed the GI side effects for me. I only use it once a week now,
>>>but I
>>>still get some GI upset occasionally on 1500mg/day. AlkaSeltzer has
>>>bicarb in
>>>it and I think this is what works.. Glucophage can cause a mild
>>>acidosis in
>>>some people, and the bicarb reverses this. I have blood tests done
>>>every 8
>>>wks and I have a mild elevation in the anion gap.. which suggests low
>>>bicarb.
>>>AlkaSeltzer Hearburn Refief has no aspirin in it for those who wish to
>>>avoid
>>>aspirin. Take care.



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