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Actos side effects? Anybody else experience this?From: Tracy (anonymous@obgyn.net)Fri, 20 Sep 2002 05:54:21 -0500 (CDT)
I had been put on 45 mg of Actos and 1500 mg. Glucophage back in early 2001 for PCOS and type 2 diabetes. After a 50 pound weight loss and significant lifestyle change, I was able to reduce the glucophage to 1000 mg of the XR formula, and the actos to 30 mg. I started having serious side effects from the actos. Very serious fluid retention in my lower legs, face, and stomach, and chronic coughing and sinus trouble. The doctor lowered me to 15 mg, and my blood sugar has held steady in tight control, but the side effects came back after a month on the lower dose. I am just not going to be able to tolerate the actos anymore at any dose. My doctor will probably increase my glucophage to 1500 mg for now, at least until I get some more weight off and the sugars are yet even more easier to control. The doctor prefers a smaller dose of the two drugs combined more than a larger dose of either. He says they work best together. Well, that may all be well and true, but I cannot live with swelling and constant coughing and postnasal drip anymore. The only alternative is diuretics and cold/sinus medication to manage the side effects of the actos, and I refuse to take two drugs to control the side effects of another. It's just too much medication. Has anybody else had these side effects with actos? Has anybody else had hair loss? I started seeing more thinning on my head when I added the actos to my treatment plan. The doctor said it is probably not related to actos but rather just general PCOS or thyroid disease related hair loss, but I am not sure. I never lost hair like this before, why now, why after the actos and not before? Anyway, I am hoping to be off of it by the end of the month, it is just not working out for me. Too bad, I had really good blood sugar control and my PCOS symptoms were all really well controlled. But frankly, I'd rather have to eat more restrictively and exercise more frequently and just deal with slightly worse PCOS symptoms than suffer the side effects of actos.
-- Tracy
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