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Re: Dr. Sam? A question for you.

From: Pat (anonymous@obgyn.net)
Fri, 28 Jun 2002 10:48:57 -0500 (CDT)


Thanks for your comments. I have seen very good response for women from Micronized progesterone, taken orally. With the development of prescription progesterone cream, this has been a real boon for women. My experience is that women have less side effects and a good response to natural progesterone. This is not always the case with provera and medroxy-progesterone-acetate. It has been good to see the development of progesteone products that more naturally act in the body as the actual chemicals do. There has also been an increase in the use of these products over the past few years with successful outcomes.

--
Pat Sonnenstuhl, ARNP, CNM, MS
Balanced Eating Support
http://home.attbi.com/~cnmpat/favlowcarbsites.htm
http://home.attbi.com/~cnmpat/siteindex.htm
PCOS Support
http://www.midwivesofwa.org/pcos.htm
http://www.midwivesofwa.org//pcosarticles.htm>
> Hi Pat,
>
>I have to defend the pharma industry. Natural progesterone (P) is hardly absorbed from the GI tract. It has been extensively researched in the early years of endocrinology (Selye, 1935) and turned out to be useless for human application. Therefore it was a tremendous breakthrough, when German organic chemists succeeded to synthetise the first orally active estrogen (ethynil-estradiol) and gestagen. The ones (norethisterone among them) that were applied in oral contraceptives were synthetised later by C. Jerassy. Only the physiochemical manipulation (micronization) of P rendered it absorbable from the GI tract. And still it is less active than the synthetic derivatives (therefore not available as a conttraceptive). And porvera is a very good synthetic choice being a close relative of the natural compound: medroxy-progesterone-acetate.
>For your info
>
>Sam
>
>> I am not Dr.  Sam, but I have used Progesterone Cream quite successfully
>> as a substitute for Provera.  As a Woman's Health Care provider, I work
>> with women to find combinations that work best for them.  Micronized
>> progesterone in tablet form, and prescription progesterone cream have
>> been more researched and more consistent in amount.  The progesteone
>> cream you can buy over the counter is less reliable, and the % of
>> progesterone will vary.  The problem is these are 'natural' products,
>> have probably been less well researched, and there isn't the same money
>> to be made with natural progesterone, as there is to be made with
>> synthetics.  Sorry to be so tough on the pharmaceutical companies, but I
>> belive this to be so.  For many years we were limited to synthetic
>> progestin with no natural products available.  It has only been through
>> consumer demand that we now have a wide variety of products, and finally
>> in many instances, natural progesterone is being used more and more
>>
>> Pat Sonnenstuhl, ARNP, CNM, MS
>> Balanced Eating Support
>> http://home.attbi.com/~cnmpat/favlowcarbsites.htm
>> http://home.attbi.com/~cnmpat/siteindex.htm
>> PCOS Support
>> http://www.midwivesofwa.org/pcos.htm
>> http://www.midwivesofwa.org//pcosarticles.htm.
>>
>> >Hello Dr.  Sam.  :) I just wanted to know what your thoughts were on
>> >natural progesterone creme.  I've read a bit about it over the past few
>> >days and was just curious to how you felt about this form of
>> >treatment(in general).
>> >
>> >Thanks for your thoughts and ideas!
>> >Tangelo ;)
>>



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