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Articles: some are gems

From: Victoria (anonymous@obgyn.net)
Wed, 26 Jun 2002 9:33:02 -0400


Lots of good articles came out yesterday. Thyroid, IR, GI index, low carb dieting, OC/BCP that mention PCOS, Phytoestrogens, fibromyalgia, HRT and diabetes.

--
Victoria

THYROID SCREENING MAY BE NEEDED FOR WOMEN OF CHILDBEARING AGEPhysicians may need to accelerate basal thyroid-stimulating hormone (TSH) screening for women in their childbearing years, Dr. Wolfgang Raber told participants at the 84th annual meeting of the Endocrine Society.http://www.medscape.com/viewarticle/436991?srcmp=wh-062102

WOMEN WITH PCOS HAVE IMPAIRED CAROTID VISCOELASTIC PROPERTIES Women with polycystic ovarian syndrome (PCOS) experience vascular dysfunction that may increase their risk of coronary artery disease and stroke, according to a rapid access report published in the July 2nd issue of Circulation. http://www.medscape.com/viewarticle/436989?srcmp=wh-062102

PHYTOESTROGENS SHOW WEAK ACTIVITY Phytoestrogens are for the most part 'rather weak' as active estrogens, researchers reported in Berlin at the 10th World Congress on Menopause. http://www.medscape.com/viewarticle/436777?srcmp=wh-062102

PHYSIOLOGIC FACTORS INVOLVED IN FIBROMYALGIA, CONTRADICTING PSYCHOGENIC ATTRIBUTION Functional magnetic resonance imaging (fMRI) and neuroendocrine studies of people with fibromyalgia reinforce the notion that altered responses to pain and exercise are physiologically based. http://www.medscape.com/viewarticle/436963?srcmp=wh-062102

IMPAIRED GLUCOSE TOLERANCE COMMON AMONG MI PATIENTS Many acute myocardial infarction patients have impaired glucose tolerance or undiagnosed diabetes, Swedish researchers report in The Lancet. http://www.medscape.com/viewarticle/437021?srcmp=meds-062102

GENETIC PREDISPOSITION AFFECTS WEIGHT GAIN WITH ANTIPSYCHOTIC USE Researchers have identified a polymorphism of the 5-hydroxytryptamine 2C (5-HT2C) receptor that is associated with weight gain related to the use of antipsychotic drugs. http://www.medscape.com/viewarticle/436767?srcmp=meds-062102

CHRONIC INFLAMMATION PREDICTS DEVELOPMENT OF TYPE 2 DIABETES More evidence that mild, chronic inflammation is associated with the development of type 2 diabetes was presented at the American Diabetes Association's scientific sessions. http://www.medscape.com/viewarticle/436775?srcmp=meds-062102

Allopathic and complementary alternatives to hormone replacement therapy -- Expert Opinion in Pharmacotherapy <a href=http://www.obgynlinx.com/thearts.cfm?artid=371981&specid=5> http://www.obgynlinx.com/thearts.cfm?artid=371981&specid=5 </a>

Management of the menopause is a rapidly growing concern due to the ageing human population. The overall female lifespan has increased over the last century and up to a third of a woman's life is now spent in menopause. To that end, significant attention has been placed on maximising the quantity and quality of life in the menopausal years ...

ORAL CONTRACEPTIVE USE AND ASSOCIATION WITH GLUCOSE, INSULIN, AND DIABETES IN YOUNG ADULT WOMEN: THE CARDIA STUDY Are OCs associated with impaired carbohydrate metabolism or increased risk of diabetes in young women? Diabetes Care 25(6):1027-1032, 2002. http://www.medscape.com/viewarticle/434446?srcmp=ms-062102

NUTS MAY LOWER RISK OF DIABETES Zinc was also found to improve insulin sensitivity. Medscape Medical News 2002 http://www.medscape.com/viewarticle/436827?srcmp=endo-062102

CHRONIC INFLAMMATION PREDICTS DEVELOPMENT OF TYPE 2 DIABETES More evidence that mild, chronic inflammation is associated with the development of type 2 diabetes was presented here Saturday at the American Diabetes Association's 62nd scientific sessions. Reuters Health Information 2002 http://www.medscape.com/viewarticle/436775?srcmp=endo-062102

Metformin & lifestyle intervention prevent Type 2 diabetes: lifestyle intervention has the greater effect -- Expert Opinion in Pharmacotherapy

<a href=http://www.endolinx.com/thearts.cfm?artid=371984&specid=16> http://www.endolinx.com/thearts.cfm?artid=371984&specid=16 </a>

Metformin caused some weight loss but to a lesser extent than the intensive lifestyle intervention. Both therapies decreased the fasting plasma glucose levels to a similar extent initially. The intensive lifestyle intervention decreased plasma glycosylated haemoglobin levels to a greater extent than metformin. Both intensive lifestyle intervention and metformin reduced the incidence of diabetes, with the lifestyle intervention having the greater effect...

Glucose and insulin responses to dietary chromium supplements: a eta-analysis -- American Journal of Clinical Nutrition

<a href=http://www.endolinx.com/thearts.cfm?artid=371915&specid=16> http://www.endolinx.com/thearts.cfm?artid=371915&specid=16 </a>

Conclusions: Data from RCTs show no effect of chromium on glucose or insulin concentrations in nondiabetic subjects. The data for persons with diabetes are inconclusive. RCTs in well-characterized, at-risk populations are necessary to determine the effects of chromium on glucose, insulin, and Hb A1c...

Glycemic index and disease -- American Journal of Clinical Nutrition

<a href=http://www.endolinx.com/thearts.cfm?artid=371934&specid=16> http://www.endolinx.com/thearts.cfm?artid=371934&specid=16 </a>

It has been suggested that foods with a high glycemic index are detrimental to health and that healthy people should be told to avoid these foods. This paper takes the position that not enough valid scientific data are available to launch a public health campaign to disseminate such a recommendation...

Glycemic index and heart disease -- American Journal of Clinical Nutrition

<a href=http://www.endolinx.com/thearts.cfm?artid=371933&specid=16> http://www.endolinx.com/thearts.cfm?artid=371933&specid=16 </a>

A diet high in carbohydrates with high glycemic indexes (GI) and glycemic load were linked to risk of coronary heart disease development in women in a large prospective study. Two cross-sectional studies showed that low-GI diets are associated with high HDL-cholesterol concentrations, especially in women. In a tightly controlled study of patients with type 2 diabetes, serum total cholesterol, LDL cholesterol, and apolipoprotein B concentrations fell more significantly after a low-GI diet than after a high-GI diet...

Glycemic index, glycemic load, and risk of type 2 diabetes -- American Journal of Clinical Nutrition

<a href=http://www.endolinx.com/thearts.cfm?artid=371931&specid=16> http://www.endolinx.com/thearts.cfm?artid=371931&specid=16 </a>

The possibility that high, long-term intake of carbohydrates that are rapidly absorbed as glucose may increase the risk of type 2 diabetes has been a long-standing controversy. Two main mechanisms have been hypothesized, one mediated by increases in insulin resistance and the other by pancreatic exhaustion as a result of the increased demand for insulin...

Glycemic index: overview of implications in health and disease -- American Journal of Clinical Nutrition

<a href=http://www.endolinx.com/thearts.cfm?artid=371930&specid=16> http://www.endolinx.com/thearts.cfm?artid=371930&specid=16 </a>

Furthermore, consumption of low-glycemicindex diets has been associated with higher HDL-cholesterol concentrations and, in large cohort studies, with decreased risk of developing diabetes and cardiovascular disease. Case-control studies have also shown positive associations between dietary glycemic index and the risk of colon and breast cancers. Despite inconsistencies in the data, sufficient, positive findings have emerged to suggest that the dietary glycemic index is of potential importance in the treatment and prevention of chronic diseases...




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