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Re: Progesterone Increasing Depression?

From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Wed, 19 Jun 2002 09:29:53 +0200


<sfmaphis@yahoo.com (susan)> 2002.06.17. 19:58:12 -5h-kor írta:

> I have been on Desogen, Ovcon 35, Ortho Tri Cyclen, and currently am on
> Lo-Ovral. My problem is that I've experienced terrible moodiness and
> cycles of depression on all of them (especially OTC- that was the
> worst!) I was reading about Yasmin and wondering if it could help, but I
> was also wondering if increasing the progesterone would increase the
> depression. I noticed that in most of the pills I've been on the
> estrogen dose is between .30-.35 and the progesterone between.15-.30,
> but on OTC the progesterone increased from .18 to .215 to .25 over the
> three week cycle. This makes me wonder if the high dosage of
> progesterone in Yasmin (it's 3.0 from what I've read) could cause
> depression? If anyone has any thoughts I'd be glad to hear them! Thanks!
>

Hi Susan,

Before asking a very difficult question, you should realize, that oral contraceptives (OCs) do not contain progesterone, which is the natural hormone produced by the placenta and the corpus luteum, but progestogens or progestins, synthetic hormones with a wide range of actions. Besides having a wide spectrum of hormonal activities, their potencies differ substantially, therefore you can't gues from the number (without dimenison !) tehir side effects (depression). For your info

Sam




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