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Re: Flutamide and Spiro vs. Glucophage XR

From: Fergus (anonymous@obgyn.net)
Fri, 19 Apr 2002 06:14:05 -0700


>----- Original Message -----
From: "mychel" <anonymous@obgyn.net> To: "Multiple recipients of list PCOS-MEDICATION" <pcos-medication@mail.medispecialty.com> Sent: Thursday, April 18, 2002 7:43 AM Subject: Flutamide and Spiro vs. Glucophage XR

> I guess my question is which of the two treatments (either Flutamide and
> Spiro. or Glucophage XR) is the better treatment plan for PCOS?

Glucophage (the normal or XR variants) with or without Spirolactone would seem to me to be preferred to Spironolactone and Flutamide. I hadn't heard of Flutamide before, so I did a Web search. It seems, like Spironolactone, it's an anti-androgen.

Glucophage is an insulin sensitizer. It treats the underlying cause of PCOS by improving your body's insulin response. The treatment you're on now will only mask some of your symptoms. You are at risk for developing PCOS complications if you don't treat the underlying cause. Glucophage XR is the time-release variant of Glucophage. Some people have found Glucophage XR easier to tolerate.

It's common to prescribe Spironolactone with Glucophage because Spironolactone can help reduce unwanted hair growth. Since you're happy with the results you've had with Spiro, you might want to discuss with your doctor continuing to take it even if switch to Glucophage.

> I have
> thought about it and it seems vain that I would opt for the Glucophage
> just to lose weight when the other two medications were giving me good
> results so far--other than weight loss.

No, it is absolutely not vain. Weight loss is only one benefit of taking Glucophage. Glucophage will also reduce your risk of developing serious complications, including diabetes.

> However, I have yet to have a
> period in the six months, so would it be possible that the Glocophage
> would be worth a try to see if it might bring one on eventually, by
> regluating my body?

Glucophage has helped my girlfriend to have almost normal periods for the first time in her life.

> I have a wonderful doctor that is giving me a lot of control in the
> decision making, so I am trying to gather information so I can make an
> informed decision on what would be best in the long run. Any help would
> be appreciated!

Has your doctor discussed diet and exercise with you? These are also important elements in keeping PCOS complications at bay.




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