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Re: Diagnosed with PCOS, and trying for 4 years to concieve

From: anonymous@obgyn.net
Sun, 31 Mar 2002 19:05:28 -0500


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>----- Original Message -----
From: Zalányi <anonymous@obgyn.net> To: Multiple recipients of list PCOS-MEDICATION <pcos-medication@mail.medispecialty.com> Sent: Sunday, March 31, 2002 3:28 PM Subject: Re: Diagnosed with PCOS, and trying for 4 years to concieve

> Hi Karen,
>
> I stand by what I said earlier. Metformin 500 first, higher dose second
and combo third and you have to wait with each step at least 3 mo before rising the dose or adding anything to it. > I am located in Hungary, as you may see from my address (.hu)
> For your info
>
> Sam
>
> > Hello Dr. Sam, may I ask if you think I should be put on both meds
> > right away and see what that does for me? And if they both do work for
> > me, will it start my period right away, or will I have a chance to get
> > pregnant before I even start a period (keeping in mind I haven't had one
> > since November of last year)? I don't really know what to expect. And
> > if I do get pregnant, do I stop taking the meds? Or continue while I am
> > pregnant? I know that this is a syndrome and it's a life long uncurable
> > one, but it's maintained by the meds.
> > Can I also please ask where you are located? I am in Marysville, WA and
> > am looking for a possible different doctor who knows a little more about
> > PCOS than my doctor now. Thank you for taking the time to write down
> > your ideas and knowledge, I greatly appreciate it!! Please write back if
> > you have time. Thank you!!
> >
> > At Fri, 29 Mar 2002, =?iso-8859-2?q?Zalányi wrote:
> > >
> > > <anonymous@medispecialty.com (Karen)> 2002.03.28. 19:33:51 -6h-kor
írta: > > >Hi Karen,
> > >
> > >There are several (typical) mistakes in your treatment.
> > >1: There is no strict dose/response relation with clomid. I.e. your
chances > > >of conceiving do not increase with increrased dose. On the opposite,
with > > >increasing doses the antiestrogen effects of clomid diminish the
thickness > > >of the endometrium, rendering it unable to accept a fertilized egg.
> > >2: It is no reason to race with metformin. To see if it works at 500
mg, > > >you have to wait one/several months. If it does not, than you increase
to > > >1000 mg and wait another month or so. After 6 mo, you add clomid and
wait > > >again. You have to consider, there is only a <10% chance of getting
pregnant > > >each month.
> > >For your (doctor's) info
> > >
> > >Sam (Ob/Gyn,RE)
> > >
>




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