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Re: Diagnosed with PCOS, and trying for 4 years to concieve
From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Sat, 30 Mar 2002 17:20:51 +0100
Hi Karen,
I stand by what I said earlier. Metformin 500 first, higher dose second and combo third and you have to wait with each step at least 3 mo before rising the dose or adding anything to it.
I am located in Hungary, as you may see from my address (.hu)
For your info
Sam
> Hello Dr. Sam, may I ask if you think I should be put on both meds
> right away and see what that does for me? And if they both do work for
> me, will it start my period right away, or will I have a chance to get
> pregnant before I even start a period (keeping in mind I haven't had one
> since November of last year)? I don't really know what to expect. And
> if I do get pregnant, do I stop taking the meds? Or continue while I am
> pregnant? I know that this is a syndrome and it's a life long uncurable
> one, but it's maintained by the meds.
> Can I also please ask where you are located? I am in Marysville, WA and
> am looking for a possible different doctor who knows a little more about
> PCOS than my doctor now. Thank you for taking the time to write down
> your ideas and knowledge, I greatly appreciate it!! Please write back if
> you have time. Thank you!!
>
> At Fri, 29 Mar 2002, =?iso-8859-2?q?Zalányi wrote:
> >
> > <anonymous@medispecialty.com (Karen)> 2002.03.28. 19:33:51 -6h-kor írta:
> >Hi Karen,
> >
> >There are several (typical) mistakes in your treatment.
> >1: There is no strict dose/response relation with clomid. I.e. your chances
> >of conceiving do not increase with increrased dose. On the opposite, with
> >increasing doses the antiestrogen effects of clomid diminish the thickness
> >of the endometrium, rendering it unable to accept a fertilized egg.
> >2: It is no reason to race with metformin. To see if it works at 500 mg,
> >you have to wait one/several months. If it does not, than you increase to
> >1000 mg and wait another month or so. After 6 mo, you add clomid and wait
> >again. You have to consider, there is only a <10% chance of getting pregnant
> >each month.
> >For your (doctor's) info
> >
> >Sam (Ob/Gyn,RE)
> >
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