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Re: Question for Dr. Sam

From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Sat, 30 Mar 2002 17:17:36 +0100


Hi Jen,

Unfortunately this is the usual way how metformin is prescribed, but not the logical one in my opinion. As in the case there is no diabetes to get checked, but insulin resistance and the consequent anovulation. As the result in case of treating anovulation would be an ovulation, I think one dose level should be maintained for several months to see if you ovulate. If not, you could increase the dose. But there is no report I know of, in which the dose of metformin was compared to the result (ovulation). In my praxis, many patients improved on 500 mg/day. For your info

Sam

> Dr. Sam, I was reading a response you wrote to someone about metformin
> doses and had a question for you. My endo started me on Metformin Feb.
> 12, I started taking 1 tablet, 500mg a day for two weeks, then I was to
> start taking two tablets a day, 1000mg a day for two weeks, then 3
> tablets, 1500mg a day for two weeks, then max out at 4 tablets, 2000mg a
> day, for as lonf as I take this medication. I have not been diagnosed
> as diabetic, or insulin resistant. From what I have read on the
> discussion boards, this seems like a high dose to me.
> Is this how it is normaly done? I don't see my endo again until the end
> of april, and as he is very difficult to get a hold of, I thought I
> would ask your opinion while I was waiting for him to return my call.
> Thanks, Jen
>




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