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Re: Diagnosed with PCOS, and trying for 4 years to concieve

From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Fri, 29 Mar 2002 07:01:31 +0100


<anonymous@medispecialty.com (Karen)> 2002.03.28. 19:33:51 -6h-kor írta: Hi Karen,

There are several (typical) mistakes in your treatment. 1: There is no strict dose/response relation with clomid. I.e. your chances of conceiving do not increase with increrased dose. On the opposite, with increasing doses the antiestrogen effects of clomid diminish the thickness of the endometrium, rendering it unable to accept a fertilized egg. 2: It is no reason to race with metformin. To see if it works at 500 mg, you have to wait one/several months. If it does not, than you increase to 1000 mg and wait another month or so. After 6 mo, you add clomid and wait again. You have to consider, there is only a <10% chance of getting pregnant each month. For your (doctor's) info

Sam (Ob/Gyn,RE)

> Tera, thank you for your response. I am still new to all of this and
> love the suport of all the women out there. It's nice to hear all the
> same stories that you are going through. (very sad to see how many
> women go through this and aren't better yet, but very comforting to hear
> that I'm not the only one) :)
> I actually started on 50mg of the clomid, then went to 100mg, then
> finally to 150mg and that's when I took a few months off to get over the
> frustations of it all. I am going on my second week of 500mg of just
> the metformin, from there my doctor said he would put me on both and see
> what that did for me. I am hoping for a change in my attitude (I get
> very moody cause of the hormone levels being so low) I am so glad I have
> a supportive husband.
> How long have you had this or been diagnosed with it?
> Are you still trying to get pregnant? (you don't have to tell if you
> don't want too, I know it's personal and it's hard to talk about it when
> someone asks). I pray for everyone all the time too, someday we will be
> able to make this allot more public than it is right now. So many women
> don't know about it at all. Nor do the doctor's. Thank you for your
> kind words! :)




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