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Re: Glucophage XR==GI side effects....help!!
From: Lori (anonymous@obgyn.net)
Sun, 24 Feb 2002 21:08:24 -0600 (CST)
I am experiencing the same prorblem with what looks like the capsules
coming out. I did a science experiment on it today, and it isn't solid
on the inside. I am wondering if it is perhaps fat that we are passing
directly? I have been taking it for about 5 months and my GI problems
have never stopped. They have gotten better as time has passed but a
regular stool is still something very rare for me. I decided that it
was better than not treating it, so I just drink plenty of water each
day and bear it, although it does get embarassing sometimes.
At Sun, 24 Feb 2002, claire wrote:
>
>At Fri, 22 Feb 2002, mrsdoubtfyre wrote:
>>
>>At Mon, 18 Feb 2002, =?iso-8859-2?q?Zalányi wrote:
>>>
>>> <madeline808@aol.com (Maddy)> 2002.02.17. 22:52:40 -6h-kor írta:
>>>Come on Maddy,
>>>
>>>If you have GI side-effects, then the substance is absorbed. It is only the outer shell you find 9-12 h later in stool. Regular metformin is even worse as for side-effects.
>>>For your info
>>>
>>>Sam
>>>Hi there
>
>Ijust wanted to let you know that I too have had great success with
>AlkaSeltzer, and within about 10 mins of taking one, all my stomach
>cramps disappear. I have also found that following a low fat diet
>incredibly successful with both the GI symptoms of met, and also weight
>loss (i've lost 24lbs in 2 months)
>
>hope you're problems improve, I know how painfull they can be, but dont
>give up, it's all worth it in the end
>
>good luck
>
>Claire
>>>> Hi there--
>>>> I'm 25 and just started on Glucophage XR. I have been taking 500 mg.
>>>> for about a week, and I am having pretty awful GI upset....diarrhea etc.
>>>> Also, i saw someone else with this problem, the capsules themselves
>>>> sometimes come out, but like nine to twelve hours later!!! Someone
>>>> replied that the medication itself is absorbed, but how can that be? I
>>>> actually checked one of the undigested capsules and there was a white
>>>> substance inside. Does anyone think regular Glucophage is easier to
>>>> digest, etc. than the Glucophage XR? I have been taking it with my
>>>> dinner....so I don' tknow what to do about the stomach upset and how
>>>> long to stick it out. I want to get up to 1500 mg.
>>>>
>>>> Any tips or advice would be greatly appreciated. I really do want to
>>>> stay on it..i was on Avandia but developed some serious edema.
>>>>
>>>> Thanks so much.
>>>>
>>>> maddy
>>>>
>>Dear Maddy: I found that an AlkaSelzer tablet taken once a day for a
>>week or
>>so removed the GI side effects for me. I only use it once a week now,
>>but I
>>still get some GI upset occasionally on 1500mg/day. AlkaSeltzer has
>>bicarb in
>>it and I think this is what works.. Glucophage can cause a mild
>>acidosis in
>>some people, and the bicarb reverses this. I have blood tests done
>>every 8
>>wks and I have a mild elevation in the anion gap.. which suggests low
>>bicarb.
>>AlkaSeltzer Hearburn Refief has no aspirin in it for those who wish to
>>avoid
>>aspirin. Take care.
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