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Re: Dr. Sam - Metformin and Actos

From: SusieQ (anonymous@obgyn.net)
Thu, 24 Jan 2002 09:26:28 -0600 (CST)


Yes, I understand that weight loss is not the goal of metformin - it's my goal though. Ha, ha. The low energy is still a problem.

If I lower the dose of metformin to 1500 mg/day, to help with energy, would the androgens increase? I do not want the androgen increase, just more energy all day.

Would combining Actos with the Metformin help with energy?

Many thanks, SusieQ

>
>Hi SusieQ,
>
>First of all, metformin is no weight drug. Decreasing your androgens is the aim of therapy, so you shouldn't do anything against it.
>
>Sam
>
>> Hello Dr. Sam,
>>
>> Thank you for your reply. I appreciate your time. Are you saying that
>> the decreasing androgens can contribute to low energy? If this is so,
>> how to treat?
>>
>> When I increase met to 2500 mg/day, I definitely have hypoglycemia. My
>> main problem is that I can not lose weight on 2000 mg/day. How could I
>> gain energy and lose weight without inducing hypoglycemia?
>>
>> Again, Thank you, SusieQ
>>
>> > Hi SusieQ,
>> >
>> >There is a ,isundeerstanding with the dose of metformin. I think it is
>> >absolutely unnecessary to increase the dose over several weeks, because the
>> >insulin imbalance is not as bad as with diabetics. Time matters more. If you
>> >improved on 2000 mg/day why to increase to 2500? The tiredness may be
>> >indicative of hypoglycaemia (low sugar) or decreasing androgens (which
>> >usually give energy, but is in excess in PCOS). I would run lab tests to
>> >clear up this problem.
>> >
>> >Sam
>> >




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