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Re: Dr. Sam - Metformin and Actos

From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Mon, 21 Jan 2002 20:28:47 +0100

Hi SusieQ,

There is a ,isundeerstanding with the dose of metformin. I think it is absolutely unnecessary to increase the dose over several weeks, because the insulin imbalance is not as bad as with diabetics. Time matters more. If you improved on 2000 mg/day why to increase to 2500? The tiredness may be indicative of hypoglycaemia (low sugar) or decreasing androgens (which usually give energy, but is in excess in PCOS). I would run lab tests to clear up this problem.

Sam

> Hi Dr. Sam,
>
> I have been taking 2000 mg/day Metformin for 15 months. I can not
> tolerate the side effects of 2500 mg/day (headache, nausea, dizziness).
> I am improving many of my symptoms, but still am tired most of the day.
>
> My RE suggested combining Actos with Metformin to improve my energy
> level. What do you think of this prescription? Do you have any other
> suggestions for my continuing tiredness?
>
> Many Thanks for your time, SusieQ
>

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