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Re: maybe Dr. Sam can help - d chiro inositolFrom: anonymous (anonymous@obgyn.net)Thu, 8 Nov 2001 06:01:23 -0600 (CST)
At Wed, 8 Nov 2000, =?iso-8859-2?q?Zalányi wrote: >How close are they to approving this for PCO? Is this d chiro inositol for ovulating or weight loss, or both? i Muriel, > >Although there is sense in your reasoning, but things are not as simple as that. The weight-insulin relation is correct (i.e. if you loose wt your IR improves), but the heart disease, atherosclerosis is not. There is another proof, that correcting IR does not result automatically in weight loss: PCOSers on Avandia and/or Actos tend to GAIN weight instead of loosing it. > >Sam > >> Hi again, >> >> OK I have been trying to work through this Glucophage thing logically, not >> medically, and here are my conclusions. >> >> If Glucophage does NOT help you to lose weight, I conclude that you do not >> have an insulin problem. How can I say that? Follow my reasoning. >> >> Say you are obese, and you have trouble losing weight. You find out that you >> have PCOS and are prescribed Glucophage to regulate your insulin levels. The >> Glucophage may or may not make you sick, and you try several different >> dosages to attempt to find what is right for you. Your motivation? To become >> healthy with lesser risks of heart disease and diabetes, AND to lose weight. >> >> So you have been on glucophage for a couple of months, and you have not lost >> a single pound. You suffer from the side effects anyways because at least >> you will become "healthy" from this drug, while at the same time feeling >> lousy with diarrhea. >> >> If you claim to have Insulin resistance, and the glucophage is supposed to >> solve that problem, then logically you WILL lose weight because your body >> will adjust accordingly, better breaking down the sugars in your system. If >> you think you have insulin resistance, and you do NOT lose any weight with >> Glucophage, then how is it unreasonable to believe that your obesity problem >> lies NOT with insulin resistance, but something else (such as over eating, >> inactivity, non-PCOS-related hormone problems). >> >> Also, if you claim to be taking Glucophage in order to become healthier and >> to reduce the risk of diabetes and heart disease, yet you do not lose any >> weight, wouldn't the risk remain the same simply because of all the fat? >> Being overweight causes diabetes, being overweight causes heart disease. So >> how in the world can you give yourself better chances if weight loss does >> NOT occur? >> >> I may be 21, but I certainly care about my health and I am insulted by >> anyone who infers that I do not. I am losing weight on Glucophage (20 pounds >> within 2 months thus far), which leads me to believe that I do in fact have >> an insulin resistance problem, especially because I have not changed my diet >> (much). >> >> My opinion on the matter is that the most important thing you can do for >> yourself and for your health is to bring your weight down from dangerous >> levels to a more normal weight range (whatever is possible for people with >> PCOS). I think if you are not doing this, glucophage is little more than a >> placebo that gives you diarrhea. >> >> Muriel >>
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