PCOS-MEDICATION Messages for November, 2001: Re: glucophage and pregnancy loss

Re: glucophage and pregnancy loss

From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Sat, 4 Nov 2000 18:49:02 -0800

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Maybe in reply to: naz: "glucophage and pregnancy loss"

Hi Naz,

While some 15% of clinical pregnancies ends up in spontaneous abortion, the rate is 2-3X higher for PCOSers. This is due to the elevated LH levels which disturb early pgy and to the disturbed glucose metabolism. As metformin reduces LH and corrects glucose metabolism its is advisable to continue it duriong the early months or longer. There is a catch however, metformin increases the risk of neural tube defects, that is why most obstetricians are afraid of continuing it during pgy. But this increased risk can be countered with extra folic acid while taking metformin. For your info

Sam

> I have been on metxr 1000mg for 6months and also on synthroid for a few
> years.Sept 26 I found out I was pregnant.My endo asked me to stop the
> met and also lowered my thyroid med .When I went for an Ultra sound at
> my ob 10 days later ,she said that the pregnancy had not progressed (not
> a viable pregnancy) and she had to do an emergency D&C. I am wondering
> if stopping met had anything to do with this.I know there are differing
> opinions about taking met during pregnany.Has anyone continued to take
> it? Please enlighten me.
>

Next message: =?iso-8859-2?q?Zalányi Sámuel ?=: "Re: Metabolife type drugs effect PCOS? (new here!)"
Previous message: =?iso-8859-2?q?Zalányi Sámuel ?=: "Re: Spiro and side effects?"
Maybe in reply to: naz: "glucophage and pregnancy loss"

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