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Re: New to the Forum
From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Sun, 22 Oct 2000 17:34:26 -0700
Hi Jan,
The frequency of miscarriage is multiple in PCOSers. Metformin is able to decrease this risk to average, therefore if your lab results support the Dx of PCOS, metformin is indicated even if you are not insulin resistant. However metformin increases the risk of neural tube defect, but this can be countered by adding folic acid (800 mcg/day) to your diet.
For your info
Sam (Ob/Gyn, RE)
> Hi everyone,
>
> This is the first time that I've posted a message to this forum, but
> I've been reading your messages for a few months now. I'm living in the
> UK and was diagnosed with PCOS in November 1999, when I was ttc without
> success. My PCOS symptons are quite monir compared to some of you, but
> my yearning for a baby is so great that the condition is causing me to
> feel very depressed.
>
> To cut a long story short, I was first put on Clomid (100mg) for 6
> months and in this time I actually conceived but unfortunately,
> miscarried quite early on. The hospital then put me on Tamoxifen but
> this did very little for me. I then had my ovaries drilled and managed
> to fall pregnant without medication (horray!!) but I once again
> miscarried. I am now back on Clomid (100mg) for 3 months and the
> hospital have told me that there is little more they can do for me if I
> don't conceive in the next three months. I am an NHS patient and they
> don't seem very interested in the fact that I've had two miscarriages
> now and it's obviously breaks my heart.
>
> I have been reading about Metformin and on my last appointment I asked
> to be put on it. I was told that this was only given to obese PCOS
> sufferers and that I didn't need it. I'm not sure how they can say this
> when I have never had an insulin restistance test done. Should I insist
> on these tests being carried out? I'm not sure how much more heart ache
> they are expecting me to go through!!
>
> If anyone in the UK is reading this then can you tell me where I might
> find a doctor in or around London or the South East of England that is
> pro Metformin because from what I have read it would seem that this is
> some sort of wonder drug for us PCOS women.
>
> Thanks for taking the time to read my rather lengthy tale!
>
> --
> Jan
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