PCOS-MEDICATION Messages for October, 2001: Re: What are my chances of conceiving on Clomid again?

Re: What are my chances of conceiving on Clomid again?

From: anonymous@obgyn.net
Fri, 19 Oct 2001 16:29:28 -0500 (CDT)

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Paula -

I don't know your exact medical situation but you might also want to try upping your dose of Metformin. Women with PCOS are usually treated starting with 1500mg/day and working up from their until their symptoms are reduced or resolved. (The maximum dose recommended by Bristol Myers Squibb, the manufacturer, is 2550mg/day.) I believe that diabetics, who take a lower dose then we do, are also started at 1000mg. It might mean better control of your hormones, insulin included, and that could lead to more frequent ovulation and a better chance at carrying your baby to term.

A recent study showed that using 1500mg Metformin and Clomid together, a full 91% of women with PCOS ovulated within 2 months! The fact that you ovulated before seems to me a strong indication that your body can do it again. TTC is such a roller coaster. I wish you luck and good health!

At Fri, 12 Oct 2001, Paula wrote: >
>Hi all,
>
>I started taking Glucophage in July. I'm taking 500 mg per day. We
>also started my first cycle of Clomid, 50 mg in July. Fortunately, we
>conceived in the first cycle. Unfortunately, we had a miscarriage at 6
>1/2 weeks. We waited through one cycle, 39 days, before trying again.
>
>I'm now on my second cycle of Clomid, again 50 mg, and it does not
>appear I will ovulate this cycle. I'm feeling somewhat discouraged.
>
>So I'm wondering, does the fact that we had some initial success with a
>low dose of Clomid give me a greater chance of conceiving again? Since I
>don't seem to be ovulating this cycle, should we increase the dose?
>
>Thanks,
>
>--
>Paula
>

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