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Re: Dr.Sam, how metformin is related to lactic acidosis

From: anita (anonymous@obgyn.net)
Fri, 21 Sep 2001 00:35:59 -0500 (CDT)

Hi,

Side effects of metformin are primarily confined to the gastrointestinal tract (abdominal discomfort and diarrhea). Lactic acidosis( another side effect of metformin) is rare. Most reported cases of lactic acidosis occur in patients with contraindications, particularly impaired renal function (>90% of cases).

-anita.

At Wed, 19 Sep 2001, =?iso-8859-2?q?Zalányi wrote: >
>Hi Sujatha,
>
>Lactic acidosis (LA) is a very rare event. It is caused by an increase of lactate levels in blood. Metformin is metabolised and excreted by the kidneys.
>
>Sam
>
>> Hello Dr.sam,
>>
>> I am worried . What is lactic acidosis and how this can be caused by
>> metformin. As far as I know it is increased lactate levels. what are
>> symptoms of it. I am experiencing now-a-days an inconvenience in obdomen
>> and left back when taking deep breath, I feel tight and pain with deep
>> breaths.and how metformin is related to renal functioning.
>>
>> thanks in advance,
>> Sujatha.
>>

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