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Re: side effect of Glucophage?--Dr. Sam

From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Wed, 5 Sep 2001 10:09:51 +0200

Hi Lauren,

Metformin shifts your metabolism into acidotic direction. There is a (little bit exagerated) warning on the label not to drink alcohol, because it too causes acidosis and the two may combine to end up in a life-theatening lactic acidosis. I know of one person who ended up with LA. For your info

Sam

> Thank you very much for your response. Could you explain it in a bit
> more detail? What exactly is acidosis, and if this is the case, is it a
> problem? Should I worry? I am not having other side effects, after two
> months on metformin, except for some continuing g.i. upset.
>
> --Lauren
> >
> >Hi Lauren and Mel,
> >
> >There are two explanations:
> >1. Breathing is regulated at 3 points in the neural system: low oxygen (as
> >on high altitude), high carbondioxyde (exercise) and low pH. The third may
> >be the clue with Lauren, as metformin may cause acidosis.
> >2. Inability to breath "deep" is a typical psychosomatic symptom...
> >For your info
> >
> >Sam (Ob/Gyn,RE)
>

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