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Re: Xenical, cholesterol and insulin resistanceFrom: Sue (anonymous@obgyn.net)Fri, 31 Aug 2001 16:26:16 -0500 (CDT)
>My endocrinologist prescribed Xenical for my high cholesterol and insulin resistance.< I'm surprised--Xenical is strictly a diet drug. It's considered a "reminder medication"--basically, if you eat "incorrectly" (as described in the pamphlet), it "reminds" you not to do it again with significantly unpleasant results. This is the medication that talks about "uncontrollable bowel movements" and "oily rectal discharge" (Sorry!!) happening when you eat outside of the recommended guidelines. It's basically negative reinforcement--if you "behave negatively," that behaviour is reinforced by the unpleasant results. By eating as they direct and taking the medication, you might lower your cholesterol, but it is not a cholesterol-lowering drug in and of itself. Only the "statin drugs" are--Zocor, Pravachol, and others. Nor is it to lower your insulin resistance--it doesn't have any properties to do that. By taking metformin (in a correct dosage), you are lowering your insulin resistance, blood sugar levels (you sound as if you might be borderline diabetic), and your cholesterol levels. When your insulin levels are in check, your testosterone comes down, and testosterone controls (for the most part) your cholesterol levels. Are you sure your dr. said the Xenical was to control your IR *&* your cholesterol? I would check on that again--met will do that on its own, and if you don't have to pay for an expensive diet drug, see if you can get out of it.
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