no subject received Sun, 15 Jul 2001 01:58:57 -0500
From: =?iso-8859-2?q?Zalányi Sámuel ?= (anonymous@obgyn.net)
Sat, 14 Jul 2001 10:18:14 +0200
<gath@fidalgo.net (Christa Wheeler)> 2001.07.13. 16:51:58 -5h-kor írta:
Hi Christa,
I keep wondering about doctors knowledge of PCOS. Naturally there is a link between miscarriage and PCOS, better to say several links.
1: The disturbed LH/FSH balance
2: Increased insulin causing increased androgens
3: Low progesterone
4: Diabetes alone increases thew risk of misc. and fetal abnormalitis
The specific treatment is metformin if you are TTC, because the other insulin sensitizers' fetal risk is unknown. I would wait with clomid at least for 6 mo, because metformin alone induces ovulation.
For your and your dr's info
Sam (Ob/Gyn, RE)
> Hi,
> I am 25 years old, have PCOS and have been struggling with infertility
> for 3 years. We had a miscarriage last year that totally devastated us
> and now are trying some new treatment. My doctor for 2 years knew
> nothing about the connection between PCOS and insulin resistance, but I
> am now with a new doctor and am on Metformin and Clomid. I have heard a
> lot about a new thing called D-Chiro-Inositol and am looking for any
> information anyone may have on that. Apparently you can get it
> naturally through food, but the actual medication that the drug company
> is trying to get approved has shown to induce normal ovulation in more
> than 85% of the women doing the studies.
> Does anyone know anything about that, or where I can sign up to get
> invovled in a group study? Also looking for information that you may
> have on the link between PCOS and miscarriage. My doctor says there is
> none, frankly I don't buy it. Why would your insulin levels suddenly be
> ok once you're pregnant. Anyone who could respond to this would be much
> appreciated.
> thanks!
>
> --
> Christa Wheeler
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