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Re: Metformin vs. Actos/Avandia ? Dr. Sam, please help

From: anonymous@obgyn.net
Sun, 3 Jun 2001 10:08:27 EDT


In a message dated 06/02/2001 6:29:30 PM Pacific Daylight Time, anonymous@medispecialty.com writes:

> As for the question about my doctor's comments on the pancreas, the way
> she explained it: Met will absorb excess insulin in the bloodstream, but
> won't inhibit production of it. So, the pancreas will continue to be
> overworked and eventually stop working.

If this was her comment, you are right.. she is not that informed on PCOS. In actuality Met does inhibit the production of insulin by the pancreas by allowing the insulin to gain entry into previously resistant receptors and to be properly used by the body, therefore, the receptors are not always signaling to the brain "HEY, we need some more insulin up here!" and the pancreas is not forced to constantly push out more. Otherwise it would get to the point where it would not be able to produce at that rate and would give out- giving us the gift of Type II diabetes. But the met DOES help with this. As far as the whole organs causing you to be dead by 40, THAT I have to say I've got a deer in the headlight look on that one. Heart disease, diabetes, and cancer I have heard of with this... organ shut down I have not (But that definately doesn't mean I'm disputing it just because I've never heard of it-Lord knows this board is constantly surprising me with new info ;-) I hope whatever the solution, you find something that works for you! Susan C. :-)




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