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Re: Dr. Sam--Question about meds interaction

From: anonymous (anonymous@obgyn.net)
Fri, 25 May 2001 14:11:38 -0500 (CDT)


Wow, that totally makes sense to me now. I had very few symptoms of PCOS prior to quitting Ortho-Tricyclen this time. I had stopped the pill in the past, but only had to induce one menses and then I was back on schedule. Minor/infrequent cysts when I was in my teens. To think I was doing good for my body with all the cancer protection the pill offers, when really I was making my PCOS worse. I was wondering why this hadn't happened before (acne, amenorrhea, weight gain, etc.), and why the PCOS would "suddenly" develop.

At Fri, 25 May 2001, =?iso-8859-2?q?Zalányi wrote: >
>Hi Mel,
>
>I exactly mean what I say: BCPs deteriorate insulin resistance. If you check the contraindications for combined types of BCPs, diabetes is one of them. Insuline resistance is the stage prior to type2 diabetes.
>Yes I am trying to say: BCPs are making insulin resistance worse. There are piles of scientific papers on this topic, most of them written in the late '70s early '80s. I think this is enough basis to warn against taking them, besides tha fact that they only mask, sometimes even deteriorate PCOS. Therefore I often suggest that progestins are better to induce periods than taking BCPs.
>For your info
>
>Sam (Ob/Gyn,RE)
>
>> --- Zalányi Sámuel <anonymous@obgyn.net> wrote:
>> > BCPs in general deteriorate the metabolic disturbance of PCOS
>> > (insulin resistance) and also decrease the benefits metformin can
>> > offer. If you can solve your contraception in other ways, you better
>> > stop BCP. Tri-cyclics are the worst among BCPs.
>>
>> I only recently re-joined the list, so I may have missed this
>> discussion, but what exactly do you mean by "deteriorate the metabolic
>> disturbance of PCOS"? Are you trying to say BCPs make insulin
>> resistance worse? How so? I've never anywhere heard anything like
>> that.
>>
>> When you talk about "worse" and "you better stop", what exactly is your
>> basis? I'm not arguing, I've just never heard that before, and I've
>> been reading up on PCOS (including these boards) for a long time. I've
>> personally been taking BCP for several years with no problems, or at
>> least none that I can notice. I take regular *non-Tri* Ortho-Cyclen,
>> and have in the past taken Nordette and Alesse. I am unable to take
>> Metformin, and it seems to me that having periods with BCP is better
>> than never having them at all -- am I *wrong* on that?
>>
>> --Mel
>>




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