PCOS-MEDICATION Messages for May, 2001: Re: Dr Sam -- about Glucophage

Re: Dr Sam -- about Glucophage

From: =?iso-8859-2?q?Zalányi Sámuel?= (anonymous@obgyn.net)
Fri, 18 May 2001 19:35:18 +0100 (MET DST)

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Reply: anonymous@obgyn.net: "Re: Dr Sam -- about Glucophage"

Hi Christa,

There is a controversy about taking glucophage during pg. Drug manufacturers tend to minimize the risk of their drugs being taken during pg, thus they set up categories for them: A is absolutely safe, B is not harmful, C potentially harmful and D is dangerous during pg. As there is not enough experience with metformin during pg they have put it into category C. The truth is that therer is some basis for cat. C, because metformin reduces the absorption of folic acid thus increasing the risk of neural tube defects. But stoping it during pg increases the risk of spontaneuos abortion. Finally you have to make a painful decision which risk is greater (I think the sp.ab. is). For your info

Sam

> Hi Dr. Sam--
>
> Do you know any PCOS women that have taken Glucophage during pregnancy?
> I'm not trying to get pregnant right now but I will be soon. My endo
> says I have to stop the Gluco as soon as I do become pregnant but I have
> many women say they chose to stay on it during pregnancy as it prevents
> miscarriages.
>
> Do you know if any harm can come to the fetus?
>
> Can't it be harmful to the fetus to have too much insulin racing around
> your blood and elevated androgens?
>
> Thanks for your time.
>
> --
> Christa :-)

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