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Re: Can Metformin stop ovulation?

From: anonymous@obgyn.net
Wed, 16 May 2001 13:08:17 -0500 (CDT)


Hi Paula, on the contrary Met or any of the insulin sensitizers cause ovulation the majority of the time. Are you sure you didn't have high LH/FHS ratios that was giving you false postitives every month with your OPk's? I would continue testing maybe it was one of those months were you wouldn't have ovulated anyway and it is just coincidental. Annovulation is one of the big problems with PCOS and though you have Ovulated in the past you may have a cyst that formed instead this month...you did say that your ovaries appeared cystic on your Ultrasound...which means that you don't always ovulate.This may just be one of those months.Also just a slight elevation in insulin can cause cysts and androgen problems so I would keep on the metformin.Some doctors don't think a slight elevation is a problem but being one of those patients that only has slight elevations myself and considered within the normal range I know that it is still causing a BIG problem with my hormones. Hope this helps eleavate some of your fears, Dona

>At Tue, 15 May 2001, Paula wrote:
>Hi,
>I was recently diagnosed with PCOS. Though most of the diagnostic
>tests, including fasting insulin and glucose, were normal my ultrasound
>confirmed that my ovaries were polycystic. I'm only slightly overweight
>(5'1", 130 lbs) but have real trouble losing weight. My only other
>symptom is slight excess body hair. But my periods have always been
>regular and last month's ultrasound confirmed that I do ovulate at least
>some of the time. BTW, I had a m/c last year and am 35 years old.
>
>My question is that since we are TTC, I take OPKs every month and always
>get a positive on day 14. But this month, I started Met on day 1 and
>have had no sign of a positive and I'm well past day 14. Could the Met
>be stopping my ovulation? Perhaps I shouldn't even be on Met since my
>insulin and glucose tests as well as androgen tests were all normal.
>Also, how could I have cysts on my ovaries when I have regular periods
>and a history of ovulation??? Any help would be appreciated.
>
>Pea




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