PCOS-MEDICATION Messages for May, 2001: Re: Diane and Spironolactone combination

Re: Diane and Spironolactone combination

From: =?iso-8859-2?q?Zalányi Sámuel?= (anonymous@obgyn.net)
Sat, 5 May 2001 17:57:20 +0100 (MET DST)

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Reply: anonymous: "Re: Diane and Spironolactone combination"

Hi Christa,

I think we have discussed this earlier and this was the point where Annette joined in and nearly had blown up the board. So once again: medical prudence dictates that you treat the causes and not the symptoms of diseases. Therefore the causal treatment of PCOS are insulin sensitizers. I accept, that the hyperandrogen symptoms maybe so bad that some of you needs symptomatic relief of acne, hair etc. For this an antiandrogen is indicated. Antiandrogens are: cyproterone acetate, finasteride. As in some countries cyproterone acetate is not available, spironolactone is prescribed, which IS NOT AN ANTIANDROGEN per se. It is a diuretic with antiandrogen side-effects. But if you are on cyprot-ac already (Diane) no further antiandrogen is needed. Besides antiandrogens need some 3-6 mo to act, which further complicates to evaluate which medication helped you with which symptoms.

Sam

> Dr. Sam --
>
> I'm getting a lot of info from many different places which say that
> sometimes the Diane is prescribed in combination with Spironolactone. I
> understand that all doctors are not in agreement with treatments but
> this is driving me crazy. I know all the information you give me is
> valuable and I very much appreciate your time.
>
> To make matters worse, I need to find a new endocrinologist because mine
> doesn't even know about the Diane.(We live in the US) But my
> dermatologist was aware of it because he is the one who told me about
> it.
>
> I'm going crazy.
>
> --
> Christa :-)
>

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