Re: Dr Sam
From: =?iso-8859-2?q?Zalányi Sámuel?= (anonymous@obgyn.net)
Thu, 3 May 2001 05:37:39 +0100 (MET DST)
Hi Christa,
I am not entitled to criticise PCOS websites, but this is clearly a misinformation. I do not know what drugs are available in Australia, so I wouldn't say this and this drug is missing. But to list Roaccutane for the treatment of acne in PCOS is a mistake. Roaccutane is a symptomatic treatment for PCOS at best.
The mechanism of action of cyproterone acetate is not reducing testosterone, but blocking its action on the receptor. Secondarily it may cause a reduction as well.
Sam
> Hi Dr. Sam--
>
> Just a note for you. At the website: http://www.posaa.asn.au (which is the
> PCOS site in Australia) under treatment for acne it says (and I quote):
>
> "There are 3 main treatments for women suffering from acne due to PCOS,
> Diane-35, Spironolactone (Aldactone) and Roaccutane. Diane-35 is an
> oral contraceptive pill with an anti-androgen, cypreterone acetate. the
> cypreterone acetate helps reduce the testosterone and therefore helps
> control acne and hirsutism of PCOS. The amount of cypreterone acetate
> in Diane-35 is quite small and if not found to be adequate to control
> the acne it can be prescribed by itself or other drugs can be used such
> as Roaccutane or Spironolactone. Spironolactone works very similarly to
> cypreterone acetate as it is also an anti androgen, it can be used to
> treat acne and hirsutism caused by high testosterone."
>
> I only write this to you to let you know that there is information out
> there which is contradictory. It's very hard for women trying to get
> information to know what to try and what not to try. This was from an
> actual PCOS web site.
>
> I'm still only taking the Diane and the Gluco as per your advice.
>
> Thank you for listening.
>
> --
> Christa :-)
>
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