PCOS-MEDICATION Messages for April, 2001: Re: For Dr. Sam about Glucocortoids

Re: For Dr. Sam about Glucocortoids

From: Zowie (anonymous@obgyn.net)
Mon, 30 Apr 2001 13:05:08 -0500 (CDT)

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Hi Christa, I'm (obviously) not Dr. Sam, but I wanted to point out that NO BCP is for IR. Where did you hear this?? The Glucophage IS, and that is also causing you to have more ovulatory cycles as well. Also, you should NEVER be on Ortho Tricyclen with having PCOS. Because it is a tri-phasic BCP (3 levels or "phases" of estrogen), it does NOT work well with us because our hormones are so out of whack to begin with. We need a STEADY, constant flow of hormones to keep us in check. Back to the BCP (Diane 35) and Glucophage---from what I've read on this board (mostly thanks to Dr. Sam), there should be no "interaction" between the 2 medications--again, they're for different purposes. The Glucophage is for your IR to help your insulin work more correctly, whereas the Diane is a BCP, but may also help with some of the symptoms from the PCOS (like the hirsutism and acne). The 2 medications seem to be a common combination outside the US (as Diane is not available here). I'm sure Dr. Sam will respond, but I just wanted to give you some insight in the meantime. A good website to check is http://www.rxlist.com . Here you can see for yourself the drug interactions and side effects (and other info) on medications. I have found it to be VERY helpful myself.

At Mon, 30 Apr 2001, Christa wrote: >
>Hi Dr. Sam --
>
>Thank you for all your responses to my questions which seem endless. I
>have stopped taking the spironolactone as you recommended and I'm
>continuing with the Diane 35 as well as the Glucophage (1500mg a day).
>
>Are the effects of the BCP on IR great enough to counter the good
>effects the Glucophage has on IR? I don't want to entirely destroy the
>benefits of the Glucophage by taking the Diane. My endocrinologist has
>always had me on both the Glucophage and some type of BCP.(usually
>orthotricyclen)
>
>I have read about Glucocorticoids being a good option to lower the male
>hormones present in the blood. Can you list some drugs that are
>Glucocorticoids? Is spironolactone or finasteride a glucocorticoid? Are
>any as strong as the Diane?
>
>Do glucocorticoids have the same effect on IR as the BCPs do?
>
>Sorry this is so long. Thank you for all your help.
>
>--
>Christa :-)
>

--
Good luck! -- Zowie :)

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