Re: Easing into Metformin slowly
From: =?iso-8859-2?q?Zalányi Sámuel?= (anonymous@obgyn.net)
Sat, 28 Apr 2001 16:20:00 +0100 (MET DST)
Hi Joy,
It is alway prudent to start a med slowly and gradually, but stopping it at 1000 mg/day seems to be somewhat overcautious. I use 500mg2X a day as a starting dose with my patients and increase it after the first cycle if needed.
Sam
> Hi - My doctor started me on Metformin this week and I was surprised at
> his doseage instructions cause I had not seen this sequencing posted in
> other messages I read. Here is what I was told:
>
> The goal is to get me to 1000 mg of met daily - taken in two doses (500
> mg each dose). To get there I do this:
>
> 1/2 pill daily for five days (meaning 250 mg/day for 5 days)
> 1/2 pill twice daily for 5 days (meaning 250 mg/twice for 500 mg/day)
> 1/2 pill three times a day for 5 days (meaning 250 mg/three times for
> 750 mg/day)
> 1 tablet twice a day thereafter (500 mg/twice for 1000 mg/day)
>
> Most posts I read speak of a total daily dosage of 1500-2000 mg
> administered in 3-4 daily doses - but this tops out with two doses for a
> total of 1000 mg. My fasting insulin was 30 (higher then normal
> certainly but lower then many I have read). It certainly sems a
> reasonable place to start but I am wondering if others went through this
> "ramping up" process to get to their desired dose.
>
> Thanks for any input you might have
>
> Joy
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