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Re: Thanks for the replies...From: Sue (anonymous@obgyn.net)Thu, 26 Apr 2001 09:30:27 -0500 (CDT)
>I do worry about it, risk of death is a pretty serious side effect to >me! I'm also on aldactone which I understand increases the risk.< I don't know where you got the information that Aldactone/spironolactone increases the risk of Lactic Acidosis, but it's not true! All aldactone does is decrease the amt of water in your body (releasing it through your kidneys)--the rest of the side effects (reduced hair loss, facial hair growth, and acne), is a side effect. If something were to increase the chances of L.A., it would be something that either a) clogged up your lungs so you couldn't breathe (usually contraindicated for living) or b) stopped up your kidneys so you couldn't excrete waste, including any lactic acid in your body (again, contraindicated for living). You get lactic acid in your body any number of ways, and you excrete it through breathing and peeing. Lactic acidosis is a build up of lactic acid due to non-functioning kidneys and/or lungs. If your kidneys and lungs are okay, then you are too. Of course, if you want to stop taking metformin based on fear, then that's your perogative. But IMHO, you're giving up a good course of treatment for something that happens to 1 in 33,000 people taking met (for reasons including and other than PCO). Consider me the 1 in 33,000 you know and wipe the worry away. Again, it's VERY RARE (I had other complications bringing on the L.A.) and really isn't something to worry about.
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