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Re: Avandia vs. Metformin

From: Dona (anonymous@obgyn.net)
Wed, 28 Mar 2001 14:50:37 -0600 (CST)


OMG!! Sue I always have had in the back of my mind that if I had not stopped taking Actos (15mg) during my last pregnancy I probably would have not misscarried at 20 1/2 weeks ( was last October). I am no Doctor but it only makes sense to me now.When I got pregnant everyone was telling me to stop taking it..my RE,I also saw a perinatologist for an amnio..he said not to take and my OB wanted me to stop..they all said they didnt know if it would cause birth defects or not and would rather I not take it. Believe me next time I will challenge them and keep taking it I am on a very low dosage anyhow. you dont know how angry this makes me.I know that my PCOS and hormone inbalances has everything to do with my misscarriages and being IR only makes the situation worse.Thanks, Dona

>At Wed, 28 Mar 2001, Sue wrote:
>>So yes Glitazones do work and you can get pregnant on them without clomid, but once your pregnant you have a lot of worries about how having PCOS will affect your pregnancy.<
>
>I recently saw a perinatologist (maternal-fetal medicine; very high risk
>OB) at the request of my RE. I was pleasantly surprised to learn that
>although I am on Actos (30 mg), I would be permitted to remain on it,
>should I get pg. The only thing (and I take a lot of stuff, including a
>steroidal inhaler for asthma) I wouldn't be allowed to continue was
>spironolactone, but I knew of its potential for birth defects in male
>babies, so that wasn't surprising at all. This dr. professed to be
>very conservative, but adheres to a policy of "although there might be a
>small risk to a baby in utero, it's likely worse for that child to have
>a mother whose hormones work to [essentially] kill it or who can't
>breathe."
>
>Anyhow, you might want to press the issue with your RE. I'm still
>surprised, but I have an inkling that the last time I miscarried, it was
>due to the insulin resistance and the whacko hormones in my system.




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