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Re: Glucovance?From: Sue (anonymous@obgyn.net)Tue, 16 Jan 2001 09:49:46 -0600 (CST)
>I saw an ad yesterday from Bristol Meyers Squibb saying that if you were taking Glucophage, you might be a candidate for Glucovance. And I'm wondering if that's more useful specifically to people with full-blown Type II diabetes rather than those of us who are IR...< Unless you are diabetic, you shouldn't need Glucovance. While met addresses the underlying problem of PCOS (IR), Glucovance is a combination met and glyburide, which is used to bring down blood sugar levels. BMS (the co. that makes both drugs) has recently combined glyburide with met, b/c most diabetics (Type II) take both drugs to lower blood sugar. And it's a new product, so it has effects on their overall bottom line and makes stockholders happy. Remember, you're taking met "off-label," which means that you're taking it not as it is traditionally prescribed or designed. Nothing wrong with that, but the co. makes ads for those who take the drug as it's designed: i.e., diabetics. BMS wouldn't be talking to those with PCOS until the FDA approves use of met specifically for us. If you are still having problems with met after one year, then you need to see your RE and request another insulin sensitizer: Avandia and Actos are the other two that are out there and don't have any side effects like met. But you can't have any liver disease and take either Avandia or Actos and if your liver is healthy, then you must have quarterly blood tests to make sure you're not causing liver damage.
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