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Re: My expericence with Glucophage - Actos, anyone?
From: Leigh (anonymous@obgyn.net)
Mon, 4 Sep 2000 11:14:27 -0500 (CDT)
Thanks for your reply. It's nice to know you are not alone. I know
what you mean by wanting to concentrate on something besides the PCOS
problem. I have been struggling with "unexplained" infertility for
seven years now and have yet to have a positive pregnancy test. I feel
like I have been on a "body watch" the last seven years trying to figure
out whether I am ovulating and how to solve my problems. The mood
swings don't help. I was so excited when I first started Glucophage
because I felt so much better (even with the GI problems). Despite the
positives of Glucophage, I was not willing to put up with running to the
bathroom at the smell of food. When my doctor was concerned about
toxicity - that was enough for me. I don't mind trying new drugs, but I
am not willing to risk cancer or damage to my body. I am thankful that
I have something new to try (Actos). The pills are MUCH smaller and I
don't feel the wild side effects of Glucophage so far. I will update
after I have been on Actos a while longer.
At Sun, 3 Sep 2000, aon wrote:
>
>Hi. My glucophage experience has been similar. i've been on it since
>October and at first it was a miracle, but after about three or four
>months it became and continues to be a stomach upset, although my moods
>are level--no depression or aggressive mood swings, but I'm lethargic.
>I'm tired, too heavy periods, and hungry all the time. I've lost
>weight, but being one of those weirdo skinny PCO'ers, that is not good.
>I am probably going to try actos or avandia and would also appreciate
>any information from fellow pco'ers who've tried one of the A drugs.
>Thanks. One of these days, I'd love to get this stuff under control, so
>I wouldn't have to think about it every day and could just focus on
>plain old living. Know what I mean?
>
>At Sun, 3 Sep 2000, Leigh wrote:
>>
>>Hello to everyone! I am new to this forum, but I have searched the
>>internet for the past year reading info on PCOS. In response to Kim and
>>Monica, my experience was mixed with Glucophage. I started Glucophage
>>last December and experienced some major changes. My energy level went
>>through the roof - so much, in fact, that I was existing on about four
>>hours of sleep a night and doing great. I also noticed an immediate
>>reduction in my facial hair and loss of PCOS acne (great feeling!). I
>>had GI problems, but assumed it was just an initial side effect and was
>>willing to tolerate it. I lost about 10 pounds, but I only weigh 118
>>pounds, so my RE doctor advised that I watch my weight loss. After six
>>months, however, the GI problems persisted and my energy level
>>normalized. The facial hair and acne reduction stayed the same. I
>>visited my primary doctor about my GI problems and he thought I was
>>toxic to Glucophage. He prescribed 15 mgs of Actos about three weeks
>>ago. My GI problems disappeared immediately. It has been three weeks
>>and I am side-effect free. However, I am wondering if Actos will reduce
>>my testosterone like Glucophage. My doctor faxed me some studies on
>>Actos, but it appears that those studies were citing results from
>>Metformin studies on PCOS. Has anyone had positive results on Actos?
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