PCOS-MEDICATION Messages for August, 2000: Re: Fixed IR, but testosterone still high

Re: Fixed IR, but testosterone still high - WHY???

From: Monica (anonymous@obgyn.net)
Sat, 26 Aug 2000 11:49:13 -0500 (CDT)

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Hi, Carrie,

I don't really have an answer for you but just wanted to say that you sound like you're right on track. I've read about everything you just mentioned. I do recall reading that pcos can be caused by high testosterone, with or with out IR. It sounds like if you were not IR you would still have PCOS. You have the *double whammy*. Was it the high testosterone or the IR that caused your PCO in the first place, who knows? I know from other PCOSers that some have to take other meds in additon to MET. They must have what you're going through. I've only been on MET for 5 weeks. In two months my doc want to retest my blood levels and if my testosterone hasn't come down, I may be in the same boat with you! Isn't this a fascinating disease to have! Good luck to you! :)Monica M.

At Fri, 25 Aug 2000, Carrie wrote: >
>Hello, I had always thought that if you fixed the underlying insulin
>resistance that in turn you would get you periods back, ovulate, etc. i
>have been on 2000mg/day Glucophage for 6 months. My latest blood work
>showed that my insulin is now normal, my sugar fine, but my testosterone
>increased again. It is still in the normal range for a female but close
>now to the high limit. I had read that the high insulin in the blood
>when it circulates through the ovaries bombards it and that results in
>the messed up hormones, high testosterone, etc. Does this mean that if
>I didn't have insulin resistance I would still naturally have a high
>testosterone. I always thought the two were linked but they seem to be
>separate in my case. I am very confused. Well, still staying on the
>Glucophage except going to 1000mg/day now to keep my insulin normal.
>Started back on the BCP and started 100mg Spironolactone to lower my
>testosterone. Hope it helps. Just wanted to know if anyone knew why
>curing the insulin resistance didn't help the hormonal aspects or if
>maybe I needed more time to let the hormones correct themselves. Thanks
>- Carrie

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