Re: Metformin anyone?
From: Amy (anonymous@obgyn.net)
Mon, 31 Jul 2000 09:23:04 -0400
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Well - to throw my 2 cents in - I am on Met and am not Insuline Resistant ... From
what my Doctor told me, Met helps to keep from becoming completely IR .... From
what I have read in journals, also, is that PCOS is actually caused from Insulin
ups and downs, not PCOS causing IR .... I have been on Met for about 3 months now
without being IR ...so I also respectfully disagree.... The point of Met is to
help "even Keel" everything to avoid hyper and hypoinsulinism. Hope everyone has
a wonderful day!!! (: Amy
"Avalos, Clara" wrote:
> Monica...
>
> It's Monday morning and I am racing through posts from the weekend... been
> following this thread with interest, though... I just wanted to send over
> some support for your assertions... From all the reading that I have been
> doing, I've come to pretty much the same conclusions that you write here in
> your message below. Thanks for putting it so well!
>
> =o) Hugs,
>
> Clara
>
> -----Original Message-----
> From: anonymous@obgyn.net [mailto:anonymous@obgyn.net]
> Sent: Sunday, July 30, 2000 8:48 AM
> To: Multiple recipients of list PCOS-MEDICATION
> Subject: Re: Metformin anyone?
>
> You are entitled to your opinion. I'm basing my opinion on previous
> posts from this forum's archives, journal articles I've read and the
> following taken from "PCOS Frequently Asked Questions" at
> http://www.inciid.org/faq/pcos4.html (InterNational Council on Infertility
> Information Dissemination):"... At least 30% of women with PCOS are
> insulin resistant, although some investigators claim a much stronger
> association exists. ...It appears that even some patients who so not
> test as being insulin resistant may benefit from these medication. Some
> doctors do give insulin-sensitizing medications to patients with PCOS,
> including lean women, whether or not they test as clearly being insulin
> resistant. Though studies are needed to firmly establish the benefit,
> many patients appear to experience improvements in symptoms and cycling.
> The cause of this improvement is unclear." Whether one is diagnosed as
> IR seems to be a mute point. We know this is a progressive disease,
> who's to say that today I'm not IR but in a few months I could be?
> Perhaps that is why people who do not officially test positive for IR
> still reep the benefits and relief that glucophage can provide. I'd
> rather take that approach then continue gaining weight dispite my
> efforts with diet and exercise and end up with type II diabetes some
> day. True, MET is not a hormone, but you can't dismiss the effects it
> has on hormones even in people without IR. If glucophage seems to help
> even non-IR people, and relatively safe, then why fight it? Why is it
> that non-IR people still have high testosterone levels and glucophage
> helps them? I think they're still working on that one. If there's one
> thing we *do* know, we don't know everything about this disease. I
> believe in order to make srtides in an attempt to tackle this disease,
> we need to be open-minded.
> Monica
>
> At Sat, 29 Jul 2000, anonymous@obgyn.net wrote:
> >
> >And what are you citing? I was in a University of Michigan Rezulin
> >study, one of the requirements was Insulin Resistance. Their info
> >specifically said that only half to 3/4s of the women w/PCOS had IR. And
> >how can the Met work on anything other than IR? For those of us with it,
> >it's the IR that causes the testosterone dysfunction. Met's not a
> >hormone, so I have no idea where you're getting this info.
> >
> >At Sat, 29 Jul 2000, Monica wrote:
> >>
> >>Stacey,
> >>I respectfully disagree. The new studies show that MET is effective in
> >>treating PCOS patients who do not show signs of insulin resistance. PCOS
> >>manifests itslef in two ways, IR and testosterone/androgen disfunction.
> >>The MET works on both things. I suggest before making such glib answers
> >>you check your facts, please.
> >>Monica
> >>At Thu, 27 Jul 2000, anonymous@obgyn.net wrote:
> >>>
> >>>But what do you think that Met will do for you? It's sole purpose in
> >>>being is to fix insulin issues. That's like giving someone with a bad
> >>>heart a new brain to fix the problem.
> >>>
> >>>At Thu, 27 Jul 2000, melissa wrote:
> >>>>
> >>>>i'm on glucophage and my doctor never checked my insulin level. We also
> >>>>fought until he gave in. he just checked my liver and kidneys first.
> good
> >>>>luck, melissa
> >>>>
> >>>>>From: Goldsngurl@aol.com (Laura)
> >>>>>Reply-To: pcos-medication@obgyn.net
> >>>>>To: Multiple recipients of list PCOS-MEDICATION
> >>>>><pcos-medication@mail.medispecialty.com>
> >>>>>Subject: Metformin anyone?
> >>>>>Date: Thu, 27 Jul 2000 16:56:13 -0500
> >>>>>
> >>>>>Hey! Is anyone currently on Metformin and not insulin resistant? I am
> >>>>>currently head to head with my doctor, but she won't budge. Pls let me
> >>>>>know!
> >>>>>
> >>>>>--
> >>>>>Thanks!
> >>>>>Laura
> >>>>>
>
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