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Re: Metformin anyone?From: Avalos (anonymous@obgyn.net)Mon, 31 Jul 2000 08:19:47 -0500
Monica... It's Monday morning and I am racing through posts from the weekend... been following this thread with interest, though... I just wanted to send over some support for your assertions... From all the reading that I have been doing, I've come to pretty much the same conclusions that you write here in your message below. Thanks for putting it so well! =o) Hugs, Clara -----Original Message----- From: anonymous@obgyn.net [mailto:anonymous@obgyn.net Sent: Sunday, July 30, 2000 8:48 AM To: Multiple recipients of list PCOS-MEDICATION Subject: Re: Metformin anyone? You are entitled to your opinion. I'm basing my opinion on previous posts from this forum's archives, journal articles I've read and the following taken from "PCOS Frequently Asked Questions" at http://www.inciid.org/faq/pcos4.html (InterNational Council on Infertility Information Dissemination):"... At least 30% of women with PCOS are insulin resistant, although some investigators claim a much stronger association exists. ...It appears that even some patients who so not test as being insulin resistant may benefit from these medication. Some doctors do give insulin-sensitizing medications to patients with PCOS, including lean women, whether or not they test as clearly being insulin resistant. Though studies are needed to firmly establish the benefit, many patients appear to experience improvements in symptoms and cycling. The cause of this improvement is unclear." Whether one is diagnosed as IR seems to be a mute point. We know this is a progressive disease, who's to say that today I'm not IR but in a few months I could be? Perhaps that is why people who do not officially test positive for IR still reep the benefits and relief that glucophage can provide. I'd rather take that approach then continue gaining weight dispite my efforts with diet and exercise and end up with type II diabetes some day. True, MET is not a hormone, but you can't dismiss the effects it has on hormones even in people without IR. If glucophage seems to help even non-IR people, and relatively safe, then why fight it? Why is it that non-IR people still have high testosterone levels and glucophage helps them? I think they're still working on that one. If there's one thing we *do* know, we don't know everything about this disease. I believe in order to make srtides in an attempt to tackle this disease, we need to be open-minded. Monica
At Sat, 29 Jul 2000, anonymous@obgyn.net wrote:
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