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Re: metforminFrom: Avalos (anonymous@obgyn.net)Wed, 21 Jun 2000 09:10:02 -0500
Hi Kristen... Well, like everything else about PCOS, the correct dosage and treatment plan for PCOS patients , using metformin, is also variable. I think almost everyone agrees that when Metformin is first taken, it should be taken in small dosages and gradually worked up to the dosage first prescribed by the doctor, in order to avoid side effects. I think, after that, both patient and doctor monitor the patient's progress to see if the Met is working at that dosage. If not, some doctors will increase the dosage, again gradually, but as far as I can tell, not to exceed 2550 mg per day. Metformin has different results with different people. Some women only need 500 mg. per day for them to start ovulating. Others need the maximum dosage. Sometimes Met does not prompt ovulation, and in those cases, women who want to get pregnant need to discuss with their doctors other options/additional medications. On the other hand, many women are able to conceive just with the Met, and after a very short time of being on it. With regard to how long we need to take it, PCOS is not exactly curable, it is controllable (think diabetes, where diabetics always have to watch what they eat and their insulin levels for the rest of their lives... same principle for PCOS). Because of that, women with PCOS will, if they want to treat the PCOS and control it, have to take some kind of medication for the rest of their lives or for as long as they want to control their PCOS. Yes, you can take Metformin if you don't want to get pregnant, just be sure to use some form of birth control. It has not been clearly determined whether or not Met can cause birth defects. From what I have read, most physicians advocate discontinuing use of it during pregnancy and nursing, however, there are a few fertility/PCOS experts out there who allow their patients to use it during pregnancy. I think, with almost any illness, there will always be varying opinions about the best treatment options, which medications work, at what dosages, for how long, under what conditions, etc. Ultimately, the determining agent is the PATIENT and the patient's body. Having a progressive, informed and caring physician can make all the difference in the world, too. Clara -----Original Message----- From: anonymous@obgyn.net [mailto:anonymous@obgyn.net Sent: Wednesday, June 21, 2000 9:45 AM To: Multiple recipients of list PCOS-MEDICATION Subject: metformin Hello everyone!!! Can someone please tell me what the correct dosages and treatment plan for metformin is?? Do you take it the rest of your life or just a little while? Is it just to get pregnant? Can I take it if I don't want to get pregnant? Does it cause birth defects if I do get pregnant and continue taking it? I've looked but I find different answers on the sites I have visited. I thought I would turn to the experts of PCOS. If you have any info on the above and other stuff, feel free to e-mail me. Thanks!
-- kristen
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