PCOS-DIET Messages for August, 2002: Re: Gonadotropin Therapy

Re: Gonadotropin Therapy

From: anonymous@obgyn.net
Wed, 28 Aug 2002 18:43:46 -0500 (CDT)

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Dear Steph

Did you doctor try you with metformin before he started clomid? IF he did not give you a good trial with just metformin first, he is wasting money and effort. Metformin (an insulin sensitising drug) is first line treatment for PCOS, particularly when there is infertility. It may also be helpful in reducing the high miscarriage rates that are seen in women with PCOS.

The usual approach would be to trial metformin for up to 6 months (at a dose rate between 500 and 2500 mg/day - start on lower dose and increase if required, until effect is seen). Then, if you don't ovulate with the metformin clomid would be added. If clomid does not work when combined with metformin (and it is effective in most, but not all cases), then gonadotropin therapy would be tried.

Sorry to be blunt, but if metformin or another insulin sensitising drug is not being used, you may not be getting your best treatment. Many women go through the gamut of fertilitiy treatment, when their doctor has not even considred the simplest treatment. Of course, metformin is cheap, and doctors will not make so much money. But that should not be their first concern, it should be the patient/client.

By the way, did your doctor check that your tubes and everything were clear?

Hope this helps.

Sally At Wed, 28 Aug 2002, anonymous@obgyn.net wrote: >
>I was diagnosed with PCOS months ago by my fertility doctor and have been
>undergoing treatment with Clomid. I had had three inseminations that have
>not been successful.
>
>Now I am starting Gonadotropin Therapy this cycle. I understand that for
>women with PCOS the chance of ovarian problems with this therapy is increased
>(along with multiple births). I was wondering if anybody has gone through
>this and if they had any problem? Was it successful?
>
>Thanks in advance,
>Steph

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