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Re: Pill/Diet...Questions Dr WadsworthFrom: drfred (anonymous@obgyn.net)Wed, 8 Aug 2001 06:38:57 -0500 (CDT)
At Tue, 7 Aug 2001, Nikki wrote: > >I would just like to ask a few things, I am glad that a UK Dr his on >this site, as there are a few things about Metformin that I can not >understand. > >you say that Met is suggested to be prescribed as a Trial treatment, but >by seing the results in the USA and so many women benifiting from Met >why not use it for women, as i am sure that even if it is a short term >treatment it might just be short term enough to get the desired results, >as with PCOS it is very difficult to loose weight, Met give you that >boost to get your body going, The reason I feel so strongly about it is >I have been diagnosed for about 7 years and doctors have tried >everything for me and nothing has helped I have been on metformin for >about 3.5months and have lost 11lbs and have had 2 normal periods, >now one thing you need to know is not even the pill help me with having >a period I would be given pill to cause a withdraw bleed and I would >bleed very lightly for about 2 days and that would be it, and in the end >would have to have a D&C. > >If i am getting these kind of results I am sure other ladies will be >getting the same fair enough maybe they wont but I am sure that I wont >be the one in a million, > >I hope you dont mind me cornering you but I find it very frustrating >that this pill is working for a lot of people in the USA and has even >helped ladies achieve pregnancy, yes I know it is not a fertility pill >but it is mentioned on the fertilty board, and on the side effects that >are listed with the pills when you get them preganancy is mentioned, > >With the NHS trying to save money this could help a lot of people and it >is not expensive, and the NHS could save lots on tests and different >drugs been used, >and in the end have happier women who dont need to suffer as much as >they used to. > >thank you for your time and I would love to hear your point of view on >this > >Thank you >Nikki Nikki, I recognise your frustration about the approach of the UK establishment regarding the use of Met. There are many drugs that are viewed differently accross the 2 sides of the Atlantic. The UK bodies have reviewed all the world literature and have simply taken a more cautious view. It is early days for Met in PCOS, nobody knows if the weight loss achieved on Met is sustainable. PCOS is obviously not a short term condition. You have lost 11lbs, is it fat, muscle or both? The underlying cause of insulin resistance is not addressed by the medication and weight loss achieved with Met may distract from the need for lifestyle and body composition changes. Mainstream medicine tends to be symptom orientated (periods, acne etc) and so less emphasis is placed on nutrition/exercise/body composition to control long term symptoms. I believe the key to unlocking PCOS lies in this area for many women. Loosing weight with PCOS can be very challenging and in the long term there might be a role for Met in its management. It is more likely to gain first use in ovulation induction (fertility). In this sense it may indeed become a 'fertility' drug. As yet a strong enough objective scientific argument for these uses has not been recognised in the UK mainstream. Best wishes Dr Fred
-- Dr Fred Wadsworth Centre for Nutritional Medicine London
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