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Re: please help
From: Lisa (anonymous@obgyn.net)
Wed, 20 Jun 2001 07:39:39 -0500 (CDT)
Virginia,
I have recently tried Glucophage (Metformin)to help reduce my weight and
better utilize my insulin. However, I had sever GI side effects, as
many do, from my understanding. The drug did help me ovulate, which is
why I stayed on it for 3 months. But finally the doctor took me off,
because all I did was vomit. I couldn't keep anything down, and I
didn't lose a pound! Talk about frustrating. But I have heard some
great stories, so if you are going to try it, I wish you the best.
At Wed, 20 Jun 2001, Virginia wrote:
>
>Apparently Metformin is good for blood clot patients and helps reduce
>weight? Anybody out there on this who has experience - your input would
>be appreciated.
>
>I sent a copy of your last answer with some questions of my own - I am
>suffering from almost daily bleeding as well as the history of blood
>clots - below is his reply. He is a very good doctor and very honest. I
>prefer the blunt truth to bull****.
>
>Glucophage is an anti-diabetic drug used in the management of Type II or
>so called late-onset diabetes. I have not heard of it's use in pure
>PCOS. Maybe it will help to control the weight aspect of PCOS. In many
>cases of PCOS there is a glusose intolerance as well, maybe that is what
>Regan is talking about. The "anti-male' hormone is well known in SA. It
>is called Androcur and is used to oppose the effects of the increased
>secretion of Androgens that cause the acne and increased hair
>growth(hirsutism) associated in some cases of PCOS. It is used on it's
>own in high doses or combined with oestrogen in a pill called Dianne 35
>which will not work for you. Androcur is not a CURE but a management
>modality and is quite expensive. It will not rectify your bleeding
>problems. There is NO cure for PCOS yet. All treatments are aimed at
>managing some of the symptoms.
>Hysterectomy will only help to stop the bleeding aspect as you will
>never again have bleeding. It is very often used for this reason in
>order to improve quality of life but will only deal with the bleeding
>aspect. One of the first treatments was a so-called wedge resection of
>the ovaries where a portion of the ovaries are removed or destroyed by
>cautery(burning). It is almost never used anymore because of less
>invasive medical management (this is mostly not for you with clotting
>problems). The only hormonal therapy that you could use with reasonable
>safety is Progestogen in the form of Depo-provera, Nur-Isterate, or
>various more expensive oral types.
>As you can see PCOS is a very complex problem mainly because it is not a
>disease but abnormal physiology. The old term for this was
>Stein-Leventhal Syndrome and one variant of this is also called
>Hyper-thecosis. Sorry that I can not be a little less honest but I do
>not believe that one should soften reality by giving false hope.
>
>--
>Cheers
>
>Virginia
>
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